146849-38-9Relevant articles and documents
Alternatives to 1-H-tetrazole in the preparation of phosphonate diesters and phosphonamidates from phosphonyl dichlorides
Maung, Jack,Mallari, Jeremy P.,Choy, Cindy J.,Berkman, Clifford E.
, p. 6497 - 6499 (2004)
5-Ethylthio-1-H-tetrazole (SET) and 4,5-dicyanoimidazole (DCI) were found to be suitable alternatives to 1-H-tetrazole for catalyzing the formation of mixed phosphonate diesters and phosphonamidates from phosphonyl dichlorides through a two-step one-pot reaction. 5-Ethylthio-1-H-tetrazole (SET) and 4,5-dicyanoimidazole (DCI) were examined as alternatives to 1-H-tetrazole to mediate the synthesis of phosphonate diesters and phosphonamidates from phosphonyl dichlorides through a two-step one-pot reaction in various organic solvents. SET and DCI were comparable to 1-H-tetrazole for catalyzing these reactions. SET afforded slightly greater yields than DCI while benzene was universally the best solvent for this reaction.