benzylmethyl phenylphosphonate

Base Information

• Chemical Name: benzylmethyl phenylphosphonate
• CAS No.: 146849-38-9
• Molecular Formula: C₁₄H₁₅O₃P
• Molecular Weight: 262.245
• Mol file: 146849-38-9.mol

Synonyms:benzylmethyl phenylphosphonate

Chemical Property of benzylmethyl phenylphosphonate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of benzylmethyl phenylphosphonate

There total 2 articles about benzylmethyl phenylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

P,P-dichlorophenylphosphine oxide (824-72-6) + methanol (67-56-1) + benzyl alcohol (100-51-6,185532-71-2) → benzylmethyl phenylphosphonate (146849-38-9)

Guidance literature:

P,P-dichlorophenylphosphine oxide; benzyl alcohol; With 1H-tetrazole; N-ethyl-N,N-diisopropylamine; In benzene; at 0 - 20 ℃; for 3h;

methanol; With N-ethyl-N,N-diisopropylamine; In benzene; for 3h; Further stages.;

DOI:10.1016/j.tetlet.2004.06.083

Reference yield:

P,P-dichlorophenylphosphine oxide (824-72-6) + methanol (67-56-1) + benzyl alcohol (100-51-6,185532-71-2) → dibenzyl phenylphosphonate (19236-61-4) + benzylmethyl phenylphosphonate (146849-38-9) + dimethyl phenylphosphonate (2240-41-7)

Guidance literature:

With 1H-tetrazole; N-ethyl-N,N-diisopropylamine; Yield given. Multistep reaction. Yields of byproduct given; 1) benzene, r.t., overnight, 2) 10 min;

DOI:10.1016/S0040-4020(01)80305-7

Reference yield: 82.0%

benzylmethyl phenylphosphonate (146849-38-9) → methyl phenylphosphonic acid (10088-45-6)

Guidance literature:

With trifluorormethanesulfonic acid; In toluene; at 120 ℃; for 24h; Sealed tube; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.joc.0c00550

upstream raw materials:

P,P-dichlorophenylphosphine oxide

methanol

benzyl alcohol

Downstream raw materials:

methyl phenylphosphonic acid