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146954-76-9

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    Cas No: 146954-76-9

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146954-76-9 Usage

General Description

N4-Benzoyl-2'-deoxy-2'-fluorocytidine is a chemical compound that belongs to the class of nucleoside analogues. It is a modified form of cytidine, a nucleoside found in DNA and RNA. N4-Benzoyl-2'-deoxy-2'-fluorocytidine is characterized by the substitution of a hydrogen atom with a fluorine atom at the 2' position and a benzoyl group at the N4 position of the cytidine molecule. N4-Benzoyl-2'-deoxy-2'-fluorocytidine has shown promising antiviral activity, particularly against viruses such as HIV and hepatitis B virus. Its unique structure gives it the potential to disrupt viral replication and could be a promising candidate for the development of new antiviral drugs.

Check Digit Verification of cas no

The CAS Registry Mumber 146954-76-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,6,9,5 and 4 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 146954-76:
(8*1)+(7*4)+(6*6)+(5*9)+(4*5)+(3*4)+(2*7)+(1*6)=169
169 % 10 = 9
So 146954-76-9 is a valid CAS Registry Number.

146954-76-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name N4-benzoyl-2 -deoxy-2 -fluorocytidine

1.2 Other means of identification

Product number -
Other names N4-benzoyl-2'-deoxy-2'-fluorocytidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:146954-76-9 SDS

146954-76-9Relevant articles and documents

Synthesis method for azvudine

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Paragraph 0085-0090, (2020/11/22)

The invention discloses a synthesis method for azvudine. The method comprises the following steps of carrying out a hydroxyl substitution reaction on a compound 4 and an iodine elementary substance toobtain a compound 5, carrying out an elimination reaction on an iodo group in the compound 5 to obtain a compound 6, reacting the compound 6 with azide under the catalysis of ICl to obtain a compound7, carrying out an iodine substitution reaction on the compound 7 and carboxylic acid to obtain a compound 8, and carrying out an amino and hydroxyl deprotection reaction on the compound 8 to obtaina compound 9, namely the alzvudine. Compared with an existing synthesis method, the synthesis method has the advantages of short synthesis route, shortened reaction time, mild reaction conditions andeasily controlled reaction process, can be used for preparing the alzvudine with the lower cost, and has a very good application prospect.

SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF

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Paragraph 0950, (2015/01/16)

Disclosed herein are nucleosides, nucleotides and analogs thereof, pharmaceutical compositions that include one or more of nucleosides, nucleotides and analogs thereof, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a disease and/or a condition, including an infection from a norovirus, with a nucleoside, a nucleotide and an analog thereof.

Modulation of CEACAM1 expression

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Page/Page column 26, (2010/02/11)

Compounds, compositions and methods are provided for modulating the expression of CEACAM1. The compositions comprise oligonucleotides, targeted to nucleic acid encoding CEACAM1. Methods of using these compounds for modulation of CEACAM1 expression and for diagnosis and treatment of disease associated with expression of CEACAM1 are provided.

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