146987-11-3Relevant academic research and scientific papers
HETEROCYCLIC KETONES AS PRE-FORMED BUILDING BLOCKS. SYNTHESIS OF (-)-SLAFRAMINE.
Szeto, Peter,Lathbury, David C.,Gallagher, Timothy
, p. 6957 - 6960 (2007/10/02)
A synthesis of lactam 2, which constitutes a formal total synthesis of (-)-slaframine 1, is described with key steps being (a) intramolecular aldol reaction of ketoaldehyde 4 to establish the indolizidine framework and (b) diastereoselective reduction of enone 5 using the Corey oxazaborolidine 7.
