1469876-41-2

Basic information

• Product Name: C₂₂H₃₀N₂O₃
• CAS NO: 1469876-41-2
• Molecular Weight: 370.492
• Mol File: 1469876-41-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₂H₃₀N₂O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₃₀N₂O₃(1469876-41-2)
• EPA Substance Registry System: C₂₂H₃₀N₂O₃(1469876-41-2)

Safety Data

• Hazardous Substances Data: 1469876-41-2(Hazardous Substances Data)

Upstream product

• 72170-91-3 ((S)-2-Methoxymethyl-pyrrolidin-1-yl)-pent-(Z)-ylidene-amine 
• 98-88-4 benzoyl chloride 

Downstream Products

• 1469876-47-8 (S)-N-(1-furan-2-yl-pentyl)benzamide 
• 54430-46-5 N-(benzoyl)-D,L-norleucine 

Relevant articles and documents

Asymmetric synthesis of α-(heteroaryl)alkylamines and α-amino acids via nucleophilic 1,2-addition of lithiated heterocycles to aldehyde SAMP-hydrazones

The asymmetric synthesis of α-(heteroaryl)alkylamines was accomplished by employing a diastereoselective nucleophilic 1,2-addition of lithiated aromatic heterocycles to aldehyde SAMP-hydrazones, followed by BH 3·THF or SmI2 promoted removal of the chiral auxiliary. The CBz or benzoyl-protected amines were obtained in good yields (40%-78%) and excellent enantiomeric excesses (ee = 88%-99%). The methodology can be applied to the synthesis of highly enantioenriched α-amino acids (ee = 90%-99%). TUeBITAK.