147149-69-7

Basic information

• Product Name: 4-[(3,4-Dihydro-2,6-dimethyl-4-oxo-5-quinazolinyl)thio]-benzoic acid
• Synonyms: 4-[(3,4-Dihydro-2,6-dimethyl-4-oxo-5-quinazolinyl)thio]-benzoic acid
• CAS NO: 147149-69-7
• Molecular Weight: 326.376
• Mol File: 147149-69-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-[(3,4-Dihydro-2,6-dimethyl-4-oxo-5-quinazolinyl)thio]-benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(3,4-Dihydro-2,6-dimethyl-4-oxo-5-quinazolinyl)thio]-benzoic acid(147149-69-7)
• EPA Substance Registry System: 4-[(3,4-Dihydro-2,6-dimethyl-4-oxo-5-quinazolinyl)thio]-benzoic acid(147149-69-7)

Safety Data

• Hazardous Substances Data: 147149-69-7(Hazardous Substances Data)

Upstream product

• 147149-87-9 5-bromo-2,6-dimethyl-3H-quinazolin-4-one 
• 147149-86-8 5-bromo-2,6-dimethylbenzo<1,3>oxazin-4-one 
• 147149-84-6 4-bromo-5-methyl-1H-indole-2,3-dione 
• 7745-91-7 3-bromo-4-methylaniline 
• 152946-39-9 4-((2,6-dimethyl-4-oxo-3,4-dihydroquinazolin-5-yl)sulfanyl)benzoic acid methyl ester 
• 147149-85-7 6-amino-2-bromo-3-methyl-benzoic acid 

Downstream Products

• 147150-02-5 Diethyl-N-<4-<(2,6-dimethyl-4-oxo-3,4-dihydroquinazolin-5-yl)sulfanyl>benzoyl>-L-glutamate 

Relevant articles and documents

ANTIPROLIFERATIVE QUINAZOLINES

Quinazoline compounds which demonstrate antiproliferative activity, such as antitumor activity, processes of preparing these compounds, pharmaceutical compositions containing these compounds, and the use of these compounds. These compounds inhibit the growth and proliferation of the cells of higher organisms and microorganisms,such as bacteria, yeasts and fungi. Preferred quinazoline compounds are capable of inhibiting the enzyme thymidylate synthase. Effects derived from the inhibition of the enzyme thymidylate synthase include those discussed above