147220-80-2Relevant articles and documents
Design, Synthesis and Anticancer Evaluation of New 7-O-Alkylation Genistein Derivatives
Ren, Yuyan,Chen, Hongfei,Yao, Xu,Yang, Zehua,Wu, Tingjuan,Guo, Yu,Xiao, Junhui,Zheng, Xing
, p. 924 - 931 (2020)
Genistein is a phytoestrogen compound which possesses multiple biological activities such as anti-cancer, while its application is limited by poor pharmacokinetic properties. Structural modification is an effective approach to get genistein derivatives wi
Identification of isoflavone derivatives as effective anticryptosporidial agents in vitro and in vivo
Stachulski, Andrew V.,Berry, Neil G.,Low, Lilian A.C.,Moores, Shelley L.,Row, Eleanor,Warhurst, David C.,Adagu, Ipemida S.,Rossignol, Jean-Fran?ois
, p. 1450 - 1454 (2007/10/03)
We report the preparation and antiparasitic activity in vitro and in vivo of a series of isoflavone derivatives related to genistein. These analogues retain the 5,7-dihydroxyisoflavone core of genistein: direct genistein analogues (2-H isoflavones), 2-car