147237-44-3Relevant articles and documents
Total Synthesis of the Trehalase Inhibitors Trehalostatin and Trehazolin, and of Their Diastereoisomers. Final Structural Confirmation of the Inhibitor
Uchida, Chikara,Yamagishi, Tatsuya,Ogawa, Seiichiro
, p. 589 - 602 (2007/10/02)
Potent trehalase inhibitors 1-4 have been synthesized, thereby establishing both the structure and the absolute configuration of the known inhibitor trehazolin 2.Compound 1, previously proposed as the structure of trehalostatin, and its diastereoisomer 3,
Syntheses of trehazolin, trehalamine, and the aminocyclitol moiety of trehazolin: Determination of absolute configuration of trehazolin
Kobayashi,Miyazaki,Shiozaki
, p. 813 - 822 (2007/10/02)
The syntheses and determination of the absolute configuration of trehazolin (1), its aglycon (trehalamine (3), and its aminocyclitol hexaacetate moiety (5) are described. An important intermediate, optically active epoxide 16α, was obtained from an 11-ste
Total Synthesis of Trehalase Inhibitor, Trehazolin
Ogawa, Seiichiro,Uchida, Chikara
, p. 173 - 176 (2007/10/02)
The total synthesis of trehalase inhibitor, trehazolin has been accomplished by coupling the optically active aminocyclopentanepentaol with α-D-glucopyranosylisothiocyanate derivative, followed by subsequent oxazoline-ring formation and removal of the pro