147283-74-7

Basic information

• Product Name: ETHYL (3-AMINO-2-OXO-1,2-DIHYDROPYRIDYL)ACETATE
• Synonyms: ETHYL (3-AMINO-2-OXO-1,2-DIHYDROPYRIDYL)ACETATE
• CAS NO: 147283-74-7
• Molecular Formula: C₉H₁₂N₂O₃
• Molecular Weight: 196.2
• Mol File: 147283-74-7.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ETHYL (3-AMINO-2-OXO-1,2-DIHYDROPYRIDYL)ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL (3-AMINO-2-OXO-1,2-DIHYDROPYRIDYL)ACETATE(147283-74-7)
• EPA Substance Registry System: ETHYL (3-AMINO-2-OXO-1,2-DIHYDROPYRIDYL)ACETATE(147283-74-7)

Safety Data

• Hazardous Substances Data: 147283-74-7(Hazardous Substances Data)

Usage

General Description

ETHYL (3-AMINO-2-OXO-1,2-DIHYDROPYRIDYL)ACETATE is a chemical compound with the molecular formula C9H11N1O3. It is a yellow crystalline solid that is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. ETHYL (3-AMINO-2-OXO-1,2-DIHYDROPYRIDYL)ACETATE is also known for its use in the manufacture of various types of drugs, including anti-infective and anti-inflammatory medications. It is important to handle ethyl (3-amino-2-oxo-1,2-dihydropyridyl)acetate with care, as it can be harmful if ingested or inhaled and can cause skin and eye irritation. Overall, this chemical plays a significant role in the production of various medical and agricultural products.

Upstream product

• 6332-56-5 3-nitropyridone 
• 6332-56-5 2-hydroxy-3-nitropyridine 
• 147283-78-1 2-(3-nitro-2-oxopyridin-1(2H)-yl)acetic acid 
• 147283-76-9 ethyl 3-nitro-2-oxo-1,2-dihydro-1-pyridylacetate 

Downstream Products

• 1177499-67-0 ethyl 2-(2'-oxo-3'-(benzylamino)pyridinyl-1'(2H)-yl)acetate 

Relevant articles and documents

A facile and efficient method for the synthesis of novel pyridone analogues by aminolysis of an ester under solvent-free conditions

A series of 15 pure novel N-alkylated pyridone derivatives have been synthesized in 73-96% yields on treatment of ethyl (2-pyridone)acetates with structurally diverse amines in an efficient aminolysis procedure under 'solvent-free' conditions.

1, 3, 4-BENZOTRIAZEPIN-2-ONE SALTS AND THEIR USE AS CCK RECEPTOR LIGANDS

This invention relates to pharmaceutically acceptable salts of compounds of formula (I) wherein: W is N or N+-O-; R2 is an optionally substituted C1 to C18 hydrocarbyl group wherein up to three C atoms may optionally be replaced by N, O and/or S atoms. R3 is -(CR11R12)m-X-(CR13R14)p-R9; m is 0, 1, 2, 3 or 4; p is 0, 1 or 2; X is a bond, -CR15=CR16-, -C≡C-, C(O)NH, NHC(O), C(O)NMe, NMeC(O), C(O)O, NHC(O)NH, NHC(O)O, OC(O)NH, NH, O, CO, SO2, SO2NH, C(O)NHNH, R9 is H ; C1 to C6 alkyl ; or phenyl, naphthyl, pyridyl, benzimidazolyl, indazolyl, quinolinyl, isoquinolinyl, tetrahydroisoquinolinyl, indolinyl, isoindolinyl, indolyl, isoindolyl or 2-pyridonyl substituted with -L-Q. R4 is an optionally substituted C1 to C18 hydrocarbyl group wherein up to three C atoms may optionally be replaced by N, O and/or S atoms ; and Such salts are useful, for example, for the treatment of gastrin related disorders.

Non-peptide αvβ3 antagonists. Part 6: Design and synthesis of αvβ3 antagonists containing a pyridone or pyrazinone central scaffold

Two novel series of small-molecule RGD mimetics containing either a substituted pyridone or pyrazinone central constraint were prepared. Modification of the β-alanine 3-substituent produced compounds that are potent and selective αvβ3 antagonists and exhibit a range of physicochemical properties.