147291-50-7

Upstream product

• 66389-80-8 tert-butyl N-[(4-cyanophenyl)methyl]carbamate 
• 162696-14-2 benzyl ((4-(((tert-butoxycarbonyl)amino)methyl)phenyl)(imino)methyl)carbamate 
• 217313-82-1 tert-butyl (4-carbamimidoylbenzyl)carbamate acetate salt 

Downstream Products

• 494836-49-6 [(4-{[((1R,3S,6S,8S,8aS)-6-Azido-6-benzyl-1-ethyl-8-methoxy-5-oxo-octahydro-indolizine-3-carbonyl)-amino]-methyl}-phenyl)-imino-methyl]-carbamic acid benzyl ester 
• 494836-44-1 [(4-{[((1R,3S,6R,8S,8aS)-6-Azido-6-cyclohex-1-enylmethyl-1-ethyl-8-methoxy-5-oxo-octahydro-indolizine-3-carbonyl)-amino]-methyl}-phenyl)-imino-methyl]-carbamic acid benzyl ester 
• 639832-56-7 (6R,8S)-{3-(allyl-benzyloxycarbonyl-amino)-6-[4-(benzyloxycarbonylamino-imino-methyl)benzylcarbamoyl]-8-methyl-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidin-8-yl}-acetic acid tert-butyl ester 
• 639831-18-8 (6S,8R)-allyl-{8-azido-6-[4-(benzyloxycarbonylamino-imino-methyl)-benzylcarbamoyl]-8-methyl-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidin-3-yl}-carbamic acid benzyl Ester 
• 308276-65-5 C₃₆H₃₄N₆O₄ 
• 749847-42-5 C₂₃H₂₈ClN₇O₃ 
• 791584-79-7 C₂₆H₃₅ClN₆O₂ 
• 741248-36-2 C₂₄H₃₁ClN₆O₂ 
• 735262-95-0 C₂₄H₃₁ClN₆O₂ 
• 708207-68-5 C₂₂H₂₇ClN₆O₂ 
• 639832-02-3 (S)-4-oxo-8,8-dipropyl-3-propylamino-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidine-6-carboxylic acid 4-carbamimidoyl-benzylamide 
• 1426440-17-6 C₂₂H₃₀N₆O₂ 
• 639832-38-5 (S)-8,8-diethyl-4-oxo-3-propylamino-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidine-6-carboxylic acid 4-carbamimidoyl-benzylamide 
• 1426440-16-5 C₂₁H₂₈N₆O₂ 

Relevant academic research and scientific papers

MASP-2 INHIBITORS AND METHODS OF USE

The present disclosure provides, inter alia, compounds with MASP-2 inhibitory activity, compositions of such compounds, and methods of making and using such compounds.

Antithrombotic formulation, process for its manufacturing, and use thereof

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