14734-27-1Relevant articles and documents
A convenient method for [14C]Carbonylation reactions
Elmore, Charles S.,Dean, Dennis C.,Melillo, David G.
, p. 1135 - 1144 (2000)
A simple, efficient method for generation of 14CO from Ba14CO3 has been developed. Reduction of 14CO2 using LiBEt3H gave [14C]formate in good yield which was treated with conc. H2SO4 to effect dehydration to 14CO. Through direct attachment of a reaction vessel containing aryl substrate and Pd(0) catalyst, [14C]carbonylation reactions were performed without the use of a mercury transfer pump. [14C]Carbonylation reactions using 14CO generated in this manner have been shown to proceed in good yield with a variety of substrates.
Synthesis of carbon-14 labelled 1,5 diaryl-[5- 14C]-1,2,3-triazolines
Matloubi, Hojatollah,Shafiee, Abbas,Saemian, Nader,Shirvani, Gholamhossein,Daha, Fariba Johari
, p. 31 - 36 (2007/10/03)
Two 1,2,3-triazoline anticonvulsants, 1-(4-methylsulphone-phenyl)-5-(4-methoxy-phenyl)-1,2,3-triazoline and 1-(4-methylsulphone-phenyl)-5-phenyl-1,2,3-triazoline, both labelled with carbon-14 in the 5-position, have been synthesized as part of a 5-step sequence. Copyright
Atorvastatin, an HMG-CoA reductase inhibitor and efficient lipid-regulating agent. Part I. Synthesis of ring-labeled [14C]atorvastatin
Woo, Peter W. K.,Hartman, Jon,Huang, Yun,Nanninga, Thomas,Bauman, Kelvin,Butler, Donald E.,Rubin, John R.,Lee, Helen T.,Huang, Che C.
, p. 121 - 127 (2007/10/03)
Pyrrole-ring labeled [14C]atorvastatin (Lipitor, CI-981), [R-(R(*),R(*))]-2(4-fluorophenyl)-β,γ-dihydroxy-5-(1-methylethyl)-3-phenyl -4-[(phenylamino)-carbonyl]-1H-[3-14C]pyrrole-1-heptanoic acid calcium salt (2:1), was synthesized i
