13057-53-9Relevant academic research and scientific papers
Atorvastatin, an HMG-CoA reductase inhibitor and efficient lipid-regulating agent. Part I. Synthesis of ring-labeled [14C]atorvastatin
Woo, Peter W. K.,Hartman, Jon,Huang, Yun,Nanninga, Thomas,Bauman, Kelvin,Butler, Donald E.,Rubin, John R.,Lee, Helen T.,Huang, Che C.
, p. 121 - 127 (1999)
Pyrrole-ring labeled [14C]atorvastatin (Lipitor, CI-981), [R-(R(*),R(*))]-2(4-fluorophenyl)-β,γ-dihydroxy-5-(1-methylethyl)-3-phenyl -4-[(phenylamino)-carbonyl]-1H-[3-14C]pyrrole-1-heptanoic acid calcium salt (2:1), was synthesized i
Synthesis of optically pure (D-phenyl[3-14C]alanine
Koltai,Alexin,Rutkai,Toth-Sarudy
, p. 977 - 982 (1998)
Lithium aluminium hydride reduction of methyl [7-14C]benzoate gave [7-14C]benzyl alcohol which was transformed (HBr, H2SO4) to [7-14C]benzyl bromide. The latter was reacted with lithium N-(bis-methylt
An efficient synthesis of isotope-labeled PD0331179 and its labeled metabolite
Zhang, Yinsheng
, p. 419 - 422 (2013/01/15)
4-[1-Methyl-2,4-dioxo-6-(3-phenyl-prop-1-ynyl)-1,4-dihydro-2H-quinazolin-3- ylmethyl]-benzoic acid, PD0331179, was under investigation as a matrix metalloproteinase-13 inhibitor. 14C-labeled and 2H-labeled PD0331179 and its 2/s
Syntheses of N-t-butyl-α-phenylnitrone-α-14C and α-(4-pyridyl-1-oxide)-N-t-butylnitrone-α-14C
Le, Diem Duy,Zhang, Yinsheng,Chien, David H.,Moravek, Josef
, p. 1119 - 1125 (2007/10/03)
N-t-Butyl-α-phenylnitrone-α-14C was prepared from benzoic-α-14C acid via benzyl alcohol in 40 - 55% yield (sp. activity: 30 mCi/mmol). α-(4-Pyridyl-1-oxide)-N-t-butylnitrone-α-14C arrived from Ba14CO3
Synthesis of 6-chloro 2(-ethylamino)-4-methyl-4-phenyl-[-4-14c]-4h,- 3,1-benzoxazine (etifoxine)
Azim, Elmostafa,Dupuy, Jean Michel,Lepage, Francis,Veyre, Annie,Madelmont, Jean Claude
, p. 907 - 914 (2007/10/03)
Carbonation of phenyl lithium with 14CO2, followed by reduction of [14CO2] benzoic acid, led to [α-14C] benzyl alcohol 3, the oxidation of which afforded the [α-14C] benzaldehyde 4. The lat
