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Spiro[chroMan-2,4'-piperidine], also known as 2,4'-Spiro[5H-chromeno[2,3-b]pyridine-5,4'-piperidine], is a unique spiro compound characterized by its chromene and piperidine ring system. It has garnered interest for its potential pharmaceutical applications, particularly in the development of novel drug molecules with diverse biological activities. Spiro[chroMan-2,4'-piperidine]'s unique structure and properties make it a promising candidate for further research and development in drug discovery and medicinal chemistry.

147372-85-8

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147372-85-8 Usage

Uses

Used in Pharmaceutical Industry:
Spiro[chroMan-2,4'-piperidine] is used as a potential scaffold for the development of new therapeutic agents due to its unique spiro-ring system and diverse biological activities.
Used in Medicinal Chemistry:
Spiro[chroMan-2,4'-piperidine] is utilized as a potential platform for the synthesis of heterocyclic compounds and pharmaceutical intermediates, contributing to the advancement of drug discovery and the development of novel drug molecules.
Used in Drug Discovery:
Spiro[chroMan-2,4'-piperidine] is employed as a promising candidate for the development of new drug molecules with diverse biological activities, offering potential applications in various therapeutic areas.

Check Digit Verification of cas no

The CAS Registry Mumber 147372-85-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,7,3,7 and 2 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 147372-85:
(8*1)+(7*4)+(6*7)+(5*3)+(4*7)+(3*2)+(2*8)+(1*5)=148
148 % 10 = 8
So 147372-85-8 is a valid CAS Registry Number.

147372-85-8Relevant academic research and scientific papers

SPIROCHROMANE DERIVATIVES

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Page/Page column 37; 44, (2020/02/06)

The invention relates to spirochromane derivatives, or pharmaceutically acceptable salts, biologically active metabolites, pro-drugs, racemates, enantiomers, diastereomers, solvates and hydrates thereof, as well as to pharmaceutical compositions containin

CHROMAN - SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS

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Page/Page column 140, (2012/09/10)

The invention relates to chroman spirocyclic piperidine amide derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

Potent 3-spiropiperidine growth hormone secretagogues

Yang, Lihu,Morriello, Greg,Prendergast, Kristine,Cheng, Kang,Jacks, Tom,Chan, Wanda W.-S.,Schleim, Klaus D.,Smith, Roy G.,Patchett, Arthur A.

, p. 107 - 112 (2007/10/03)

Systematic SAR studies of the different regioisomers and homologues of the spiro(indane-1,4'-piperidine) moiety in the growth hormone secretagogue L-162,752 are presented. Among them, spiro(3H-1-benzopyran-2,3'-piperidine) was found to afford secretagogue

Substituted piperidinylpropanols

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, (2008/06/13)

Compounds having the formula STR1 and the pharmaceutically acceptable salts thereof, wherein n is 0, 1 or 2; R1 is alkanoyl; and R2 is STR2 R3 is alkyl; R4 is cyano or hydroxy; R5 is hydroxy or alkano

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