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(17beta)-3-oxoestr-4-en-17-yl benzoate, commonly known as estradiol benzoate, is a synthetic version of the hormone estrogen. It is a steroid hormone that acts on estrogen receptors in the body, leading to a range of physiological effects such as development and maintenance of female reproductive tissues, regulation of the menstrual cycle, and maintenance of bone density. It is typically administered through injection and acts as a prodrug, meaning it is converted to estradiol in the body, leading to its hormonal effects.

1474-55-1

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1474-55-1 Usage

Uses

Used in Hormone Replacement Therapies:
(17beta)-3-oxoestr-4-en-17-yl benzoate is used as a hormone replacement therapy for the treatment of menopausal symptoms. It helps alleviate symptoms such as hot flashes, night sweats, and vaginal dryness, providing relief and improving the quality of life for postmenopausal women.
Used in Oncology:
In the field of oncology, (17beta)-3-oxoestr-4-en-17-yl benzoate is used for the treatment of certain types of breast cancer, particularly those that are hormone receptor-positive. It can help slow down or stop the growth of cancer cells by targeting estrogen receptors and disrupting the hormonal balance that fuels tumor growth.
Used in Orthopedics:
(17beta)-3-oxoestr-4-en-17-yl benzoate is also used in orthopedics for the treatment of osteoporosis. It helps maintain bone density and strength, reducing the risk of fractures and improving overall bone health.
It should be noted that (17beta)-3-oxoestr-4-en-17-yl benzoate should be used cautiously and under the supervision of a medical professional, as it can have potential side effects and interactions with other medications.

Check Digit Verification of cas no

The CAS Registry Mumber 1474-55-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,7 and 4 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1474-55:
(6*1)+(5*4)+(4*7)+(3*4)+(2*5)+(1*5)=81
81 % 10 = 1
So 1474-55-1 is a valid CAS Registry Number.

1474-55-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name [(8R,9S,10R,13S,14S,17S)-13-methyl-3-oxo-2,6,7,8,9,10,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl] benzoate

1.2 Other means of identification

Product number -
Other names UNII-1665A8I95W

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1474-55-1 SDS

1474-55-1Relevant academic research and scientific papers

SYNTHESIS OF 3,4-13C2 STEROIDS

Yuan, Sun-Shine

, p. 279 - 290 (2007/10/02)

A-ring enollactones 1a, 1b or 9 derived from 4-cholesten-3-one, testosterone benzoate or 3-oxo-4-estren-17β-yl benzoate were condensed with acetyl chloride to give intermediates 2a, 2b or 10. 2a and 2b were cyclized by acid or base to give 3,4-1

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