(17beta)-3-oxoestr-4-en-17-yl benzoate

Base Information

• Chemical Name: (17beta)-3-oxoestr-4-en-17-yl benzoate
• CAS No.: 1474-55-1
• Molecular Formula: C25H30 O3
• Molecular Weight: 378.511
• Mol file: 1474-55-1.mol

Synonyms:Estr-4-en-3-one,17b-hydroxy-, benzoate(6CI,7CI,8CI); 17b-Hydroxyestr-4-en-3-onebenzoate; NSC 19858; Nandrolone benzoate

Chemical Property of (17beta)-3-oxoestr-4-en-17-yl benzoate

Chemical Property:

• Vapor Pressure: 4.93E-11mmHg at 25°C
• Boiling Point: 523°Cat760mmHg
• Flash Point: 226.3°C
• Density: 1.17g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (17beta)-3-oxoestr-4-en-17-yl benzoate

There total 6 articles about (17beta)-3-oxoestr-4-en-17-yl benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

19-nortestosterone (434-22-0) + benzoyl chloride (98-88-4) → nandrolone benzoate (1474-55-1)

Guidance literature:

In pyridine;

DOI:10.1016/0039-128X(82)90147-7

Reference yield:

3-methoxy-17-hydroxyestra-2,5(10)-diene (1091-93-6) → nandrolone benzoate (1474-55-1)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous HCl

2: pyridine

With pyridine; hydrogenchloride;

DOI:10.1021/ja01602a054

Reference yield:

17β-Benzoyloxy-3β-formyloxy-androst-5-en-19-saeure (14413-35-5) → nandrolone benzoate (1474-55-1)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. Na₂CO₃

2: (i) CrO₃, H₂SO₄, (ii) aq. HCl

With sodium carbonate;

DOI:10.1248/cpb.15.27

upstream raw materials:

19-nortestosterone

benzoyl chloride

benzoic acid anhydride

3-methoxy-17-hydroxyestra-2,5⁽¹⁰⁾-diene

Downstream raw materials:

17β-benzoyloxy-5-oxo-3,5-seco-A-nor-estran-3-oic acid

3-acetoxy-17β-benzoyloxy-estra-3,5-diene

17β-benzoyloxy-4-chloro-estr-4-en-3-one

17β-benzoyloxy-5α-estran-3-one