147410-35-3Relevant academic research and scientific papers
Direct alkylation of 1-azabicyclo[1.1.0]butanes
Gianatassio, Ryan,Kadish, Dora
, p. 2060 - 2063 (2019)
The facile synthesis of functionalized azetidines has been an ongoing challenge. Here, we report a general method to directly alkylate 1-azabicyclo[1.1.0]butane (ABB) with organometal reagents in the presence of Cu(OTf)2 to rapidly prepare bis-
Regioselective rhodium(I)-catalyzed hydroarylation of protected allylic amines with arylboronic acids
Tsui, Gavin Chit,Menard, Frederic,Lautens, Mark
supporting information; experimental part, p. 2456 - 2459 (2010/07/06)
A novel regioselective rhodium(I)-catalyzed hydroarylation of unactivated alkenes with arylboronic acids is described. The catalytic system employs [Rh(COD)OH]2 and BINAP to effect the addition of various arylboronic acids to protected allylic amines. The regioselectivity was found to be highly dependent on the protecting group, favoring the linear addition product with up to 92% yield and >20:1 regioselectivity.
A new type of ketolides bearing an N-aryl-alkyl acetamide moiety at the C-9 iminoether synthesis and structure-activity relationships
Nomura, Takashi,Iwaki, Tsutomu,Yasukata, Tatsuro,Nishi, Koichi,Narukawa, Yukitoshi,Uotani, Koichi,Hori, Toshihiko,Miwa, Hideaki
, p. 6615 - 6628 (2007/10/03)
A new type of ketolides, bearing an N-aryl-alkyl acetamide moiety at the C-9 iminoether and a cyclic carbonate at the C-11,12 position was prepared and the antibacterial activities of the compounds were evaluated. Some of the derivatives showed potent ant
