97308-23-1

Usage

Uses

Used in Organic Synthesis:
1-Aziridinecarboxylic acid, 1,1-dimethylethyl ester (9CI) is used as a reagent in the preparation of substituted indolines and carbazoles through benzyne-mediated cyclization-functionalization reactions. Its presence in these reactions facilitates the formation of complex molecular structures, which are essential in the development of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1-Aziridinecarboxylic acid, 1,1-dimethylethyl ester (9CI) is utilized as a key intermediate in the synthesis of various drug candidates. Its ability to participate in cyclization reactions allows for the creation of novel molecular scaffolds with potential therapeutic properties.
Used in Agrochemical Industry:
Similarly, in the agrochemical industry, 1-Aziridinecarboxylicacid,1,1-dimethylethylester(9CI) is employed as a reagent for the synthesis of bioactive molecules with pesticidal or herbicidal properties. Its involvement in the formation of complex ring systems can lead to the development of new and more effective agrochemical products.

Upstream product

• 371-41-5 4-Fluorophenol 
• 26690-80-2 2-(N-tert-butoxycarbonylamino)ethanol 
• 96628-67-0 2-(tert-butoxycarbonylamino)ethyl methanesulfonate 
• 39684-80-5 2-(tert-butoxycarbonylamino)ethyl bromide 

Downstream Products

• 138847-36-6 {2-[(2-Benzylsulfanyl-ethyl)-methyl-amino]-ethyl}-carbamic acid tert-butyl ester 
• 97308-25-3 (3,3,3-Triphenyl-propyl)-carbamic acid tert-butyl ester 
• 202929-16-6 {2-[(2-tert-Butoxycarbonylamino-ethyl)-(2-tritylsulfanyl-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester 
• 139878-16-3 Thiobenzoic acid S-{2-[(2-tert-butoxycarbonylamino-ethyl)-methyl-amino]-ethyl} ester 
• 161490-19-3 N-(2-t-Boc-aminoethyl)-1-methylhydrazine 
• 1273546-88-5 tert-butyl 2-bromo-4-methoxyphenethylcarbamate 
• 1394248-15-7 tert-butyl 6-methoxyindoline-1-carboxylate 
• 1428963-59-0 tert-butyl 6-methoxy-7-(4-methoxyphenyl)indoline-1-carboxylate 
• 1428963-60-3 tert-butyl 6-methoxy-7-(4-(trifluoromethyl)phenyl)indoline-1-carboxylate 
• 1428963-61-4 tert-butyl 7-(4-bromophenyl)-6-methoxyindoline-1-carboxylate 
• 1428963-46-5 tert-butyl 7-deuterio-6-methoxyindoline-1-carboxylate 
• 1428963-63-6 tert-butyl 6-methoxy-7-(phenylethynyl)indoline-1-carboxylate 
• 1428963-66-9 tert-butyl 2-methoxy-1-(4-methoxyphenyl)-9H-carbazole-9-carboxylate 
• 147410-35-3 tert-butyl (3-(o-tolyl)propyl)carbamate 

Relevant academic research and scientific papers

Protected Chloroethyl and Chloropropyl Amines as Conformationally Unrestricted Annulating Reagents

The purpose of this letter is to document the use of protected chloroethyl and chloropropyl amines as conformationally unrestricted ambiphilic reagents that undergo annulation reactions with Michael acceptors. This reaction is wide in scope and utilizes r

Microwave assisted fast and clean conversion of mesylate to azide: Synthesis of (1S,2R/1R,2S)-1-azido-2-carbocyclic amines as immediate precursors to versatile 1,2-cis-diamines

An efficient and rapid conversion of mesylate to azide under microwave irradiation has been carried out. It proceeds through inversion of configuration from chiral mesylates to provide optically pure cis-azides, immediate precursors of vicinal-cis-1,2-dia

Development of a scalable synthesis of a nonbasic inhibitor of the serine protease tryptase

A chromatography-free process for the synthesis of a bis(benzimidazole)difluoromethane inhibitor of the serine protease tryptase is described. This synthesis features the introduction of the gem-difluoro moiety using the electrophilic fluorinating reagent N-fluoro-bis(phenylsulfonimide) as well as the stepwise introduction of both benzimidazole rings. A protocol for the destruction of reactive, process-related substances produced in the synthesis is also presented.