147438-60-6Relevant articles and documents
Stereoselective Total Synthesis of Antitumor Macrolide (+)-rhizoxin D
Jiang, Yueheng,Hong, Jian,Burke, Steven D.
, p. 1445 - 1448 (2007/10/03)
A convergent, stereoselective total synthesis of the macrolide antitumor agent rhizoxin D is described. (+)-DIPCI-promoted asymmetric aldol reaction, Evans-Tishchenko 1,3-diol synthesis, modified Julia coupling, and Horner-Wadsworth-Emmons reactions are featured.
The first total synthesis of the antitumor macrolide rhizoxin: Synthesis of the key building blocks
Nakada, Masahisa,Kobayashi, Susumu,Iwasaki, Shigeo,Ohno, Masaji
, p. 1035 - 1038 (2007/10/02)
The construction in optically pure form of the key building blocks, arising from our retro synthetic analysis of the antitumor macrolide rhizoxin is described.