14754-42-8Relevant articles and documents
An Efficient Synthesis of 2-Substituted Benzimidazoles via Photocatalytic Condensation of o-Phenylenediamines and Aldehydes
Kovvuri, Jeshma,Nagaraju, Burri,Kamal, Ahmed,Srivastava, Ajay K.
, p. 644 - 650 (2016)
A photocatalytic method has been developed for the efficient synthesis of functionalized benzimidazoles. This protocol involves photocatalytic condensation of o-phenylenediamines with various aldehydes using the Rose Bengal as photocatalyst. The method was found to be general and was successfully employed for accessing pharmaceutically important benzimidazoles by the condensation of aromatic, heteroaromatic and aliphatic aldehydes with o-phenylenediamines, in good-to-excellent yields. Notably, the method was found to be effective for the condensation of less reactive heterocyclic aldehydes with o-phenylenediamines.
An easy one-step photocatalytic synthesis of 1-aryl-2-alkylbenzimidazoles by platinum loaded TiO2 nanoparticles under UV and solar light
Selvam,Swaminathan
experimental part, p. 3386 - 3392 (2011/06/28)
One-pot synthesis of disubstituted benzimidazoles from N-substituted 2-nitroanilines or 1,2-diamines with 3-12 nm-sized platinum particles loaded on the TiO2 using solar and UV-A light is described. 1-Aryl-2-alkylbenzimidazoles from 2-nitrodiphenylamines are formed by combined redox photocatalytic reaction, condensation and catalytic dehydrogenation on Pt-TiO2. In case of diamines, this reaction is proceeded by Pt-TiO2 assisted photocatalytic oxidation of an alcohol and a catalytic dehydrogenation of the intermediate on the surface of platinum nanoparticles. In both cases product formation was achieved by tandem photocatalytic and catalytic reactions on Pt-TiO2.
ORGANOLITHIUM AND ORGANOSODIUM COMPOUNDS OF N-SUBSTITUTED 2-ALKYLBENZIMIDAZOLES
Tertov, B.A.,Bogachev, Yu.G.,Koshchienko, Yu.V.,Suvorova, G.M.,Tsupak, E.B.,et al.
, p. 868 - 872 (2007/10/02)
Organolithium and organosodium compounds of 1,2-dimethyl-, 1-methyl-2-ethyl-,1-methyl-2-propyl-, and 1-phenyl-2-methylbenzimidazole, containing the metal in the alkyl group at position C(2), were obtaind by metallation.It was found that metallation can be complicated by the addition of metalling reagent at the C=N bond of the heterocycle.It was shown that the obtained organometallic compounds can be used for the synthesis of various derivatives of benzimidazole.