147596-63-2

Upstream product

• 2163-44-2 diethyl 2-cyclohexylmalonate 
• 108-85-0 1-bromocyclohexane 
• 62116-54-5 sodium diethyl methylmalonate 
• 105-53-3 diethyl malonate 
• 124-38-9 carbon dioxide 
• 5452-75-5 ethyl 2-cyclohexylacetate 

Downstream Products

• 7697-58-7 Ethyl 2-cyclohexylprop-2-enoate 
• 1335213-34-7 [2-(4-chloro-phenyl)-2,4,5,6-tetrahydro-cyclopentapyrazol-3-yl]-cyclohexyl-acetic acid pentafluorophenyl ester 
• 1335213-37-0 6-{2-[2-(4-chloro-phenyl)-2,4,5,6-tetrahydro-cyclopentapyrazol-3-yl]-2-cyclohexyl-ethoxy}-nicotinic acid methyl ester 
• 1335213-36-9 methanesulfonic acid 2-[2-(4-chloro-phenyl)-2,4,5,6-tetrahydro-cyclopentapyrazol-3-yl]-2-cyclohexyl-ethyl ester 
• 1335213-33-6 [2-(4-chloro-phenyl)-2,4,5,6-tetrahydro-cyclopentapyrazol-3-yl]-cyclohexyl-acetic acid 
• 1335213-32-5 2-[2-(4-chloro-phenyl)-2,4,5,6-tetrahydro-cyclopentapyrazol-3-yl]-2-cyclohexyl-ethanol 
• 1335213-31-4 [2-(4-chloro-phenyl)-2,4,5,6-tetrahydro-cyclopentapyrazol-3-yl]-cyclohexyl-acetic acid ethyl ester 
• 1335213-30-3 2-cyclohexyl-3-oxo-3-(2-oxo-cyclopentyl)-propionic acid ethyl ester 
• 1335213-17-6 2-[2-(4-chloro-phenyl)-2,4,5,6-tetrahydro-cyclopentapyrazol-3-yl]-2,N-dicyclohexyl-acetamide 
• 1335213-15-4 4-{2-[2-(4-chloro-phenyl)-2,4,5,6-tetrahydro-cyclopentapyrazol-3-yl]-2-cyclohexyl-ethoxy}-3,5-dimethyl-benzoic acid 
• 1335213-14-3 4-{2-[2-(4-chloro-phenyl)-2,4,5,6-tetrahydro-cyclopentapyrazol-3-yl]-2-cyclohexyl-ethoxy}-3,5-dimethyl-benzoic acid methyl ester 
• 409099-31-6 3-benzotriazol-1-yl-2-cyclohexyl-3-oxo-propionic acid ethyl ester 
• 136825-41-7 (2-Cyclohexyl-propyl)-triphenyl-phosphonium; iodide 
• 136317-05-0 (3aR,4R,6R,6aR)-4-((Z)-3-Cyclohexyl-but-1-enyl)-6-methoxy-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole 

Relevant academic research and scientific papers

Nitration of α,β-unsaturated esters. Evidence for positive charge build-up adjacent to carbonyl carbon

Reactive intermediates formed in the nitration of certain α,β-unsaturated esters with nitronium tetrafluoroborate exhibit behaviour expected of highly reactive α-carbonyl cations. Three diagnostic reaction types have been observed which indicate the presence of these destabilised cations: (i) trapping in a Ritter reaction, (ii) cyclopropane formation from propyl cations, (iii) Wagner-Meerwein migration of alkyl groups. Semi-empirical calculations of the relative gas-phase stabilities of the proposed intermediate cations are useful in rationalising the observed chemistry.

An improved procedure for α-methylenation of lactones

A variety of γ-butyrolactones, as well as a δ-valerolactone and an ester, have been efficiently converted to their α-methylene derivatives by using an improved decarboxylative methylenation procedure, which is simpler and more general than the previously