147598-40-1

Upstream product

• 64-17-5 ethanol 
• 74421-63-9 ethyl D-mannonate 
• 1198-69-2 D-glucono-1,4-lactone 
• 90-80-2 D-Glucono-1,5-lactone 
• 526-95-4 gluconic acid 

Downstream Products

• 3118-85-2 D-gluconamide 
• 70093-09-3 5,5-Dimethyl-3-hydroxy-2-cyclohexenon-1-gluconylhydrazon 
• 98924-91-5 1-(α-Methyl-phenethyliden)-2-D-gluconoyl-hydrazin 
• 86427-84-1 3-(D-gluco-pentahydroxypentyl)-6-phenyl-1,2,4-triazolo<3,4-a>phthalazine 
• 1393804-90-4 1-[6-(2,4,6-trimethylphenyl)-[1,2,4]triazolo[3,4-a]phthalazin-3-yl]pentane-1,2,3,4,5-pentaol 
• 130538-65-7 6-benzyl-3-(D-gluco-pentahydroxypentyl)-1,2,4-triazolo<3,4-a>phthalazine 

Relevant academic research and scientific papers

Precursors for the synthesis of substituted 1,3,4-thiadiazole C- nucleosides, analogues of tiazofurin and related compounds

The synthesis of 2-substituted 1,3,4-thiadiazole C-glycosides is described by building a heterocyclic system at the aldehyde end of a series of sugar derivatives. Acid catalyzed dehydration of the polyhydroxylic chain resulted in C-nucleoside, an analogue of tiazofurin.

MAOS of D-gluconic acid, D-glucono-1,4- and 1,5-lactones, esters, hydrazides, and benzimidazoles thereof

Microwave-assisted organic synthesis (MAOS) of D-gluconic acid can be efficiently done by oxidation of D-glucose with bromine water, upon irradiation with microwave (MW). It was also used for the conversion of D-gluconic acid to ethyl D-gluconate, D-glucono-1,4- and 1,5-lactones, gluconyl hydrazide, and gluconyl phenylhydrazide in yields comparable to those obtained by conventional methods, but in much shorter times. A convenient microwave-mediated condensation of D-gluconic acid with o-phenylenediamines provided the respective acyclonucleoside benzimidazole in short time and good yield.

Gluconyl hydrazides

Southern army worm metamorphosis can be interrupted and certain microorganisms, as for example, bacteria, fungi, molds and algae, can be inhibited by contact with an effective growth-inhibiting concentration of gluconic acid hydrazides of the group consisting of the N-(lower alkyl) gluconyl hydrazides.