1476048-38-0Relevant academic research and scientific papers
Diversity-oriented approach to novel spirocyclics via enyne metathesis, diels-alder reaction, and a [2+2+2] cycloaddition as key steps
Kotha, Sambasivarao,Ali, Rashid,Tiwari, Arti
, p. 1921 - 1926 (2013)
A simple protocol for the synthesis of indane-based spirocyclics has been developed via enyne metathesis, Diels-Alder reaction, and a [2+2+2] cycloaddition as key steps starting from indane-1,3-dione. The key diene building block was assembled by enyne metathesis. In this sequence, rongalite is used as a green reagent to prepare the sultine intermediate, which is a useful precursor to generate the transient diene.
