1476068-47-9

Upstream product

• 1476068-60-6 methyl 4-(2,6-dimethoxyphenyl)-2,4-dioxobutyrate 
• 81090-34-8 4-bromo-2-isopropyl-aniline 
• 643-28-7 2-isopropylaniline 

Downstream Products

• 1279881-34-3 1-(4-bromo-2-isopropylphenyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazole-3-carboxylic acid 
• 1476064-46-6 2-({[1-(4-bromo-2-isopropylphenyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazole-3-yl]carbonyl}amino)adamantane-2-carboxylic acid 
• 1476068-51-5 tert-butyl N-{[1-(4-bromo-2-isopropylphenyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl}-L-leucinate 
• 1476068-48-0 N-{[1-(4-bromo-2-isopropylphenyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl}-L-leucine 
• 1476068-49-1 2-{[(5-(2,6-dimethoxyphenyl)-1-{4-[(heptylamino)carbonyl]-2-isopropylphenyl}-1H-pyrazol-3-yl)carbonyl]amino}adamantane-2-carboxylic acid 
• 790187-59-6 2-[({5-(2,6-dimethoxyphenyl)-1-[4-({[3-(dimethylamino)propyl]amino}carbonyl)-2-isopropylphenyl]-1H-pyrazol-3-yl}carbonyl)amino]adamantane-2-carboxylic acid 
• 184162-64-9 2-[({5-(2,6-dimethoxyphenyl)-1-[4-({[3-(dimethylamino)propyl](methyl)amino}carbonyl)-2-isopropylphenyl]-1H-pyrazol-3-yl}carbonyl)amino]adamantane-2-carboxylic acid 
• 1476068-50-4 N-{[5-(2,6-dimethoxyphenyl)-1-(4-{[[3-(dimethylamino)propyl](methyl)amino]carbonyl}-2-isopropylphenyl)-1H-pyrazol-3-yl]carbonyl}-L-leucine 
• 1476068-52-6 tert-butyl N-{[5-(2,6-dimethoxyphenyl)-1-(4-{[[3-(dimethylamino)propyl](methyl)amino]carbonyl}-2-isopropylphenyl)-1H-pyrazol-3-yl]carbonyl}-L-phenylalaninate 
• 1476068-53-7 tert-butyl O-(tert-butyl)-N-{[5-(2,6-dimethoxyphenyl)-1-(4-{[[3-(dimethylamino)propyl](methyl)amino]carbonyl}-2-isopropylphenyl)-1H-pyrazol-3-yl]carbonyl}-L-tyrosinate 
• 1476068-54-8 tert-butyl N-{[5-(2,6-dimethoxyphenyl)-1-(4-{[[3-(dimethylamino)propyl](methyl)amino]carbonyl}-2-isopropylphenyl)-1H-pyrazol-3-yl]carbonyl}-L-valinate 
• 1476068-55-9 di-tert-butyl N-{[5-(2,6-dimethoxyphenyl)-1-(4-{[[3-(dimethylamino)propyl](methyl)amino]carbonyl}-2-isopropylphenyl)-1H-pyrazol-3-yl]carbonyl}-L-glutamate 
• 1476068-56-0 N-{[5-(2,6-dimethoxyphenyl)-1-(4-{[[3-(dimethylamino)propyl](methyl)amino]carbonyl}-2-isopropylphenyl)-1H-pyrazol-3-yl]carbonyl}-L-phenylalanine 
• 1476068-57-1 N-{[5-(2,6-dimethoxyphenyl)-1-(4-{[[3-(dimethylamino)propyl](methyl)amino]carbonyl}-2-isopropylphenyl)-1H-pyrazol-3-yl]carbonyl}-L-tyrosine 

Relevant academic research and scientific papers

DIAGNOSIS, TREATMENT AND PREVENTION OF NEUROTENSIN RECEPTOR-RELATED CONDITIONS

The present invention describes a compound of formula (I) which can be used in the diagnosis, treatment or prevention of neurotensin receptor-related conditions such as tumors and hematological malignancies.

Efficient synthesis of heterocyclic neurotensin receptor ligands by microwave-assisted aminocarbonylation

Marking the heterocyclic neurotensin receptor antagonist SR142948A as a lead compound, the development of an efficient and a practical synthetic route to heterocyclic aryl carboxamides is reported. Thus, a highly efficient and flexible access to these carboxamides was elaborated by taking advantage of microwave-assisted aminocarbonylation reaction mediated by Mo(CO)6, Herrmann's palladacycle, [(t-Bu)3PH]BF4, and DBU.