147664-41-3

Basic information

• Product Name: pyrrolidino-benzylphenoxyethanamine
• Synonyms: pyrrolidino-benzylphenoxyethanamine;Pyrrolidine, 1-[2-[4-(phenylMethyl)phenoxy]ethyl]-;1-[2-(4-benzylphenoxy)ethyl]pyrrolidine
• CAS NO: 147664-41-3
• Molecular Formula: C19H23 N O
• Molecular Weight: 281.39
• Mol File: 147664-41-3.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 419.6°Cat760mmHg
• Flash Point: 123.1°C
• Appearance: /
• Density: 1.061g/cm³
• Vapor Pressure: 3E-07mmHg at 25°C
• Refractive Index: 1.569
• CAS DataBase Reference: pyrrolidino-benzylphenoxyethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: pyrrolidino-benzylphenoxyethanamine(147664-41-3)
• EPA Substance Registry System: pyrrolidino-benzylphenoxyethanamine(147664-41-3)

Safety Data

• Hazardous Substances Data: 147664-41-3(Hazardous Substances Data)

Usage

Description

Pyrrolidino-benzylphenoxyethanamine, also known as bromantane, is a synthetic compound belonging to the class of adamantane derivatives. It is a stimulant and anxiolytic drug with potential nootropic effects, used to enhance physical and mental performance. Bromantane is believed to modulate the levels of dopamine and serotonin in the brain, potentially improving mood, energy levels, and cognitive function.

Uses

Used in Pharmaceutical Industry:
Pyrrolidino-benzylphenoxyethanamine is used as a central nervous system stimulant and anxiolytic for its potential mood-enhancing, energy-boosting, and cognitive function-improving properties.
Used in Sports:
Pyrrolidino-benzylphenoxyethanamine is used as a doping agent in sports due to its stimulant properties, although its use and distribution may be restricted in some countries due to its potential for abuse and dependence.

InChI:InChI=1/C19H23NO/c1-2-6-17(7-3-1)16-18-8-10-19(11-9-18)21-15-14-20-12-4-5-13-20/h1-3,6-11H,4-5,12-16H2

Upstream product

• 101-53-1 p-benzylphenol 
• 123-75-1 pyrrolidine 
• 165683-41-0 2-(4-benzylphenoxy)ethylbromine 
• 85983-26-2 2-(4-benzylphenoxy)ethanol 
• 297174-87-9 (4-benzyl-phenyl)-(2-chloro-ethyl)-ether 
• 60225-65-2 2-[4-(phenylmethyl)phenoxy]ethyl 4-methylbenzenesulfonate 
• 7250-67-1 1-(2-chloroethyl)pyrrolidine hydrochloride 

Relevant articles and documents

SKIN PIGMENTATION MODIFIERS TO DARKEN OR LIGHTEN THE SKIN

The present invention relates to a method for changing the pigmentation of a skin, a mucous membrane or hair with a compound of general formula (I), a cosmetic use of said compound of general formula (I), to cosmetic compositions comprising said compound of general formula (I), and to new depigmenting agents.

Pyrrolidine and piperidine analogues of SC-57461A as potent, orally active inhibitors of leukotriene A4 hydrolase

The synthesis and biological evaluation of a series of functionalized pyrrolidine- and piperidine-containing analogues of our lead LTA4 hydrolase inhibitor, SC-57461A, is described. A number of compounds showed excellent potency in our in vitro

Structure-activity relationship studies on 1-[2-(4- phenylphenoxy)ethyl]pyrrolidine (SC-22716), a potent inhibitor of leukotriene A4 (LTA4) hydrolase

Leukotriene B4 (LTB4) is a pro-inflammatory mediator that has been implicated in the pathogenesis of a number of diseases including inflammatory bowel disease (IBD) and psoriasis. Since the action of LTA4 hydrolase is the rate-limiting step for LTB4 production, this enzyme represents an attractive pharmacological target for the suppression of LTB4 production. From an in- house screening program, SC-22716 (1, 1-[2-(4- phenylphenoxy)ethyl]pyrrolidine) was identified as a potent inhibitor of LTA4 hydrolase. Structure-activity relationship (SAR) studies around this structural class resulted in the identification of a number of novel, potent inhibitors of LTA4 hydrolase, several of which demonstrated good oral activity in a mouse ex vivo whole blood assay.