147666-82-8

Basic information

• Product Name: thunberginol F
• Synonyms: thunberginol F
• CAS NO: 147666-82-8
• Molecular Formula: C₁₅H₁₀O₅
• Molecular Weight: 270.2369
• Mol File: 147666-82-8.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 547.1°Cat760mmHg
• Flash Point: 213.7°C
• Appearance: /
• Density: 1.597g/cm³
• Vapor Pressure: 1.4E-12mmHg at 25°C
• Refractive Index: 1.793
• CAS DataBase Reference: thunberginol F(CAS DataBase Reference)
• NIST Chemistry Reference: thunberginol F(147666-82-8)
• EPA Substance Registry System: thunberginol F(147666-82-8)

Safety Data

• Hazardous Substances Data: 147666-82-8(Hazardous Substances Data)

Usage

Definition

ChEBI: An isobenzofuranone that is 2-benzofuran-1(3H)-one substituted by a hydroxy group at position 7 and a 3,4-dihydroxybenzylidene group at position 3. It has been isolated from the roots of Scorzonera judaica.

InChI:InChI=1/C15H10O5/c16-10-5-4-8(6-12(10)18)7-13-9-2-1-3-11(17)14(9)15(19)20-13/h1-7,16-18H/b13-7-

Upstream product

• 151698-58-7 N,N-diethyl-2-methoxy-6-[2-(3,4-dimethoxyphenyl)-1-oxoethyl]benzamide 
• 1212-35-7 2-(3,4-dimethoxyphenyl)-N,N-dimethylacetamide 
• 51674-10-3 N,N-diethyl-2-methoxybenzamide 
• 183619-72-9 2-[(E)-2-(3,4-Dimethoxy-phenyl)-vinyl]-6-methoxy-benzoic acid methyl ester 
• 155005-24-6 8,3',4'-trimethylstilbene-2-carboxylic acid 
• 73274-87-0 3-hydroxy-7-methoxy-3H-isobenzofuran-1-one 
• 147666-87-3 (3Z)-7-methoxy-3-[(3,4-dimethoxyphenyl)methylene]-1(3H)-isobenzofuranone 

Downstream Products

• 147666-87-3 (3Z)-7-methoxy-3-[(3,4-dimethoxyphenyl)methylene]-1(3H)-isobenzofuranone 

Relevant articles and documents

One-step synthesis of isocoumarins and 3-benzylidenephthalides via ligandless pd-catalyzed oxidative coupling of benzoic acids and vinylarenes

A straightforward synthetic method for the preparation of isocoumarins and 3-benzylidenephthalides via C-H olefination and oxidative coupling of readily available benzoic acids and vinylarenes was developed. The directing effect of the substituents on the benzoic acid allows for the synthesis of both types of lactone in pure form.

Facile synthesis of thunberginol F

A new and convenient synthesis of (Z)-3-(3,4-dihydroxybenzylidene)-7-hydroxyphthalide (5) is described starting from 3-hydroxy-7-methoxyphthalide (1).

Synthesis of 3-substituted isocoumarins and related natural products

Several N,N-diethyl-2-acylmethylbenzamides (6) were prepared from N,N- diethyl-2-toluamides (4), and the ketoamides (6) were easily cyclized to the corresponding 3-substituted isocoumarins (8) by heating in acetic acid or xylene. This simple procedure was