14772-40-8

Basic information

• Product Name: (10α)-1-Oxo-5,6-secocholest-2-en-6-oic acid methyl ester
• Synonyms: (10α)-1-Oxo-5,6-secocholest-2-en-6-oic acid methyl ester
• CAS NO: 14772-40-8
• Molecular Formula: C₂₈H₄₆O₃
• Molecular Weight: 430.66304
• Mol File: 14772-40-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (10α)-1-Oxo-5,6-secocholest-2-en-6-oic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (10α)-1-Oxo-5,6-secocholest-2-en-6-oic acid methyl ester(14772-40-8)
• EPA Substance Registry System: (10α)-1-Oxo-5,6-secocholest-2-en-6-oic acid methyl ester(14772-40-8)

Safety Data

• Hazardous Substances Data: 14772-40-8(Hazardous Substances Data)

Upstream product

• 14993-76-1 3β-acetoxy-6-oxa-7a-homocholest-4-en-7-one 
• 104596-45-4 3β-acetoxy-cholest-4-en-6-one 
• 67-56-1 methanol 
• 104527-35-7 5,6-seco-5-oxo-3,4-cholesten-6-oic acid 

Relevant articles and documents

Epoxidation and Baeyer-Villiger Oxidation of γ-Hydroxy-αβ-unsaturated Ketones on Exposure to m-Chloroperbenzoic Acid

Treatment of 3β- and 3α-hydroxy-(acetoxy-)cholest-4-en-6-one and of 6β- and 6α-hydroxy-(acetoxy-)cholest-4-en-3-one with MCPBA gives two types of product, depending on the initial site of the peroxy acid attack.Attack at the carbonyl group gives a Baeyer-Villiger rearrangement leading first to enol lactones and then by epoxidation of the latter to epoxy lactones.Alternatively, attack at the double bond gives epoxy ketones which can subsequently undergo a Baeyer-Villiger rearrangement leading to epoxy lactones.With one exception (3α-hydroxycholest-4-en-6-one), the Baeyer-Villiger oxidation of the enone is the dominant process.Epoxidation of the double bond is suppressed in the presence of an axial 3α- or 6β-acetoxy group.