14776-43-3Relevant academic research and scientific papers
NHC-catalyzed regiodivergent syntheses of difunctionalized 3-pyrazolidinones from α-bromoenal and monosubstituted hydrazine
Yu, Chenxia,Shen, Shide,Jiang, Ligen,Li, Jing,Lu, Yumiao,Li, Tuanjie,Yao, Changsheng
supporting information, p. 9149 - 9155 (2017/11/14)
A formal [3 + 2] annulation of α-bromoenal with monosubstituted hydrazine could give 1,5 or 2,5-difunctionalized 3-pyrazolidinone regiodivergently by tuning the structure of the N-Heterocyclic Carbene (NHC) catalyst. Moderate to high yields, mild reaction conditions, good regioselectivity and potential biological significance of the final product have made this protocol attractive for the assembly of 3-pyrazolidinone.
Facile and highly regiospecific synthesis of 2-aryl-substituted pyrazolidin-3-ones from α,β-unsaturated N-acylbenzotriazoles and arylhydrazines
Wang, Xiaoxia,Wang, Wencun,Wen, Yihang,He, Liang,Zhu, Xiangming
experimental part, p. 3223 - 3228 (2009/05/07)
The bis-addition of arylhydrazines to α,β-unsaturated N-acylbenzotriazoles to form heterocyclic compounds was achieved in refluxing THF by using triethylamine as promoter. The reaction was highly regioselective and various 2-aryl-substituted pyrazolidin-3
