147778-03-8Relevant articles and documents
In vivo activity of an azole series of CCR2 antagonists
Smethurst, Chris A.,Bevan, Nicola,Emmons, Amanda,Mookherjee, Claudette,Moores, Kitty,Peace, Simon,Piercy, Val,Watson, Steve P.,Zippoli, Mara,Brooks, Carl,Gough, Peter J.,Philp, Joanne
, p. 7252 - 7255,4 (2012)
Optimisation of a series of biaryl sulphonamides resulted in the identification of compound 7 which demonstrated dose-dependent and strain-specific inhibition of monocyte recruitment in a thioglycollate-induced peritonitis model of inflammation.
In vivo activity of an azole series of CCR2 antagonists
Smethurst, Chris A.,Bevan, Nicola,Brooks, Carl,Emmons, Amanda,Gough, Peter J.,Mookherjee, Claudette,Moores, Kitty,Peace, Simon,Philp, Joanne,Piercy, Val,Watson, Steve P.,Zippoli, Mara
, p. 7252 - 7255 (2013/01/15)
Optimisation of a series of biaryl sulphonamides resulted in the identification of compound 7 which demonstrated dose-dependent and strain-specific inhibition of monocyte recruitment in a thioglycollate-induced peritonitis model of inflammation.
Nitroquinolone derivatives
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, (2008/06/13)
A class of optionally 4-substituted 3-nitro-2-oxo-1,2,3,4-tetrahydroquinoline derivatives are selective non-competitive antagonists of NMDA receptors and/or are antagonists of AMPA receptors, and are therefore of utility in the treatment of conditions, su