922711-45-3Relevant academic research and scientific papers
In vivo activity of an azole series of CCR2 antagonists
Smethurst, Chris A.,Bevan, Nicola,Emmons, Amanda,Mookherjee, Claudette,Moores, Kitty,Peace, Simon,Piercy, Val,Watson, Steve P.,Zippoli, Mara,Brooks, Carl,Gough, Peter J.,Philp, Joanne
supporting information, p. 7252 - 7255,4 (2012/12/12)
Optimisation of a series of biaryl sulphonamides resulted in the identification of compound 7 which demonstrated dose-dependent and strain-specific inhibition of monocyte recruitment in a thioglycollate-induced peritonitis model of inflammation.
In vivo activity of an azole series of CCR2 antagonists
Smethurst, Chris A.,Bevan, Nicola,Brooks, Carl,Emmons, Amanda,Gough, Peter J.,Mookherjee, Claudette,Moores, Kitty,Peace, Simon,Philp, Joanne,Piercy, Val,Watson, Steve P.,Zippoli, Mara
supporting information, p. 7252 - 7255 (2013/01/15)
Optimisation of a series of biaryl sulphonamides resulted in the identification of compound 7 which demonstrated dose-dependent and strain-specific inhibition of monocyte recruitment in a thioglycollate-induced peritonitis model of inflammation.
BENZENESULFONAMIDE INHIBITOR OF CCR2 CHEMOKINE RECEPTOR
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Page/Page column 32, (2010/11/25)
Disclosed are compounds of formula (I): or a pharmaceutically acceptable salt thereof, or a solvate thereof, or a combination thereof, as well as compositions of methods of use of the compound, wherein R1, R2, R3, and m ar
