150869-44-6Relevant articles and documents
A Convenient Formal [4+2] Heterocylization Route to Bis(triflyl)tetrahydroquinolines
Lázaro-Milla, Carlos,Almendros, Pedro
supporting information, p. 13534 - 13538 (2021/08/13)
We report the sustainable and efficient synthesis of a new type of quinoline derivatives bearing one or two SO2CF3 groups. The protocol is metal-, catalyst- and irradiation-free, involves the use of readily available and stable precursors, and avoids the formation of side products. Also, the mild conditions of the process allow the tolerance of a wide range of functional groups.
In vivo activity of an azole series of CCR2 antagonists
Smethurst, Chris A.,Bevan, Nicola,Emmons, Amanda,Mookherjee, Claudette,Moores, Kitty,Peace, Simon,Piercy, Val,Watson, Steve P.,Zippoli, Mara,Brooks, Carl,Gough, Peter J.,Philp, Joanne
supporting information, p. 7252 - 7255,4 (2012/12/12)
Optimisation of a series of biaryl sulphonamides resulted in the identification of compound 7 which demonstrated dose-dependent and strain-specific inhibition of monocyte recruitment in a thioglycollate-induced peritonitis model of inflammation.
BENZENESULFONAMIDE INHIBITOR OF CCR2 CHEMOKINE RECEPTOR
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Page/Page column 31, (2010/11/25)
Disclosed are compounds of formula (I): or a pharmaceutically acceptable salt thereof, or a solvate thereof, or a combination thereof, as well as compositions of methods of use of the compound, wherein R1, R2, R3, and m ar
