147849-87-4

Upstream product

• 19533-08-5 1-(2-acetylphenoxy)-2,3-epoxypropane 
• 75-64-9 tert-butylamine 
• 118-93-4 o-hydroxyacetophenone 

Downstream Products

• 147849-89-6 5-(2-Acetylphenoxymethyl)-3-tert-butyloxazolidin-2-one 
• 98441-41-9 6-<2-(3-tert-Butylamino-2-hydroxypropoxy)phenyl>-3(2H)-pyridazinone 
• 147849-88-5 2'-<2-Acetoxy-3-propoxy>acetophenone 
• 147849-84-1 6-<2-(3-tert-Butyl-2-oxo-5-oxazolidinylmethoxy)phenyl>-4,5-dihydro-4-hydroxy-3(2H)-pyridazinone 

Relevant academic research and scientific papers

Synthesis and In Vitro Pharmacological Evaluation of 5-(Alkoxymethyl)-2-(3-alkylamino-2-hydroxypropoxy)phenylethanones Related to Acebutolol and Celiprolol

The structure–activity relationships of 13 analogs of aryloxyaminopropanol type derived from 2-hydroxyphenylethanone as potential β-blockers are described. The synthesized compounds possess an isopropyl or a tert-butyl group in the hydrophilic part of the

One-pot preparation of 6-substituted 3(2H)-pyridazinones from ketones

A one-pot process for the preparation of 6-phenyl-3(2H)-pyridazinone from acetophenone and glyoxylic acid has been investigated and shown to have wide utility in the preparation of 6- and 5,6-substituted 3(2H)-pyridazinones. Limitations to the process encountered with 2'-hydroxyacetophenone and with basic hetero-aromatic ketones have been overcome, and the processes described offer the rapid and efficient synthesis of many 6-substituted pyridazinones from readily available ketones.