147976-18-9Relevant articles and documents
Facile synthetic route to (2S,3S)-3-amino-2-hydroxy-4-phenylbutyric acid and its derivatives, the key intermediates for HIV protease inhibitors
Lei, Lijun,He, Xuchang,Bai, Donglu
, p. 1535 - 1540 (2007/10/03)
A facile and efficient route to (2S,3S)-3-amino-2-hydroxy-4-phenylbutyric acid and its derivative (4S,5S)-4-benzyl-5-hydroxymethyl oxazolidin-2-one is presented. N-phthaloyl protected L-phenylalanine 1 was treated with thionyl chloride followed by hydroge
Process for the production of a β-amino alcohol
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, (2008/06/13)
A process for producing 2-?3(S)-amino-2-(R)-hydroxyl-4-phenyl butyl!-N-tert,butyl decahydro-(4aS,8aS)-isoquinoline-e(S)-carboxamide of the formula (I) via 3(S)-?lower alkoxy carbonyl amino, phenoxy carbonyl amino or benzyl oxycarbonyl amino!-2-hydroxy-4-phenyl butyric acid and process for producing said acid.
Enantiomerically pure 3-amino-2-hydroxy and 5-amino-4-hydroxy acids from D-isoascorbic acid
Melon, D.,Gravier-Pelletier, C.,Merrer, Y. Le,Depezay, J. C.
, p. 585 - 593 (2007/10/02)
The chirospecific synthesis of 3-amino-2-hydroxy aldehyde or acid units is an important issue in the context of synthetic strategies directed towards the construction of biologically relevant target molecules such as amino sugars, antibiotics, enzyme inhi