14799-04-3

Upstream product

• 3185-99-7 Methyl p-tolyl sulfone 
• 67-64-1 acetone 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 110-05-4 di-tert-butyl peroxide 

Downstream Products

• 1421914-39-7 2-methyl-1-tosylpropan-2-yl acetate 
• 89647-15-4 1-(2-Dodecylsulfanyl-2-methyl-propane-1-sulfonyl)-4-methyl-benzene 
• 89647-16-5 1-(2-Benzylsulfanyl-2-methyl-propane-1-sulfonyl)-4-methyl-benzene 
• 89647-13-2 1-(2-Butylsulfanyl-2-methyl-propane-1-sulfonyl)-4-methyl-benzene 
• 89647-18-7 1-(2-Isobutylsulfanyl-2-methyl-propane-1-sulfonyl)-4-methyl-benzene 
• 89647-17-6 1-(2-Isopropylsulfanyl-2-methyl-propane-1-sulfonyl)-4-methyl-benzene 

Relevant academic research and scientific papers

A novel synthesis of aryl methyl sulfones and β-hydroxysulfones from sodium sulfinates and di-tert-butyl peroxide in H2O medium

A novel and convenient synthetic route for aryl methyl sulfones and β-hydroxysulfones was developed via the radical reaction between sodium sulfinates and di-tert-butyl peroxide (DTBP). Without any catalysts and additives, the synthetic process could be smoothly carried out to afford the target products in good to excellent yields in H2O medium, demonstrating its promising application. In the present system, H2O could act not only as a green solvent but also as a reactant.

Method for selectively compounding aryl methyl sulphone and belta-hydroxy sulphone derivative

The invention discloses a method for selectively compounding an aryl methyl sulphone and belta-hydroxy sulphone derivative. The method has the advantages that sulfinic acid sodium salt and di-tert-butyl peroxide serve as raw materials, water serves as green reaction solvent, additives and catalysts are not needed, and the aryl methyl sulphone and belta-hydroxy sulphone derivative is obtained through control of reaction temperature selectivity. The method has the advantages of mild reaction condition, simplicity in operation, low cost, environment friendliness, high product selectivity, high yield and the like, and has practical application value.

Coupling reaction of magnesium alkylidene carbenoids with α-sulfonylallyllithiums: An efficient route to multi-substituted vinylallenes

A variety of vinylallenes were successfully synthesized from 1-chlorovinyl p-tolyl sulfoxides and allyl or vinyl sulfones. Allyl and vinyl sulfones served as α-sulfonylallyllithium sources were prepared from carbonyl compounds in three or four steps in good overall yields. The coupling reaction of α-sulfonylallyllithiums with magnesium alkylidene carbenoids, which were generated from 1-chlorovinyl p-tolyl sulfoxides and isopropylmagnesium chloride, afforded multi-substituted vinylallenes in up to 88% yield. Georg Thieme Verlag KG Stuttgart · New York.

New synthesis of allylidenecyclobutanes by the reaction of cyclobutylmagnesium carbenoids with vinyl sulfones

The reaction of cyclobutylmagnesium carbenoids, which were generated from 1-chlorocyclobutyl p-tolyl sulfoxides with EtMgCl via the sulfoxide-magnesium exchange reaction at low temperature, with carbanions derived from vinyl sulfones with n-BuLi or LDA re

ARYL VINYL SULFONES AS THIOL PROTECTIVE GROUP

Phenyl vinyl sulfone and p-tolyl isobutenyl sulfone are convenient reagents for protecting SH groups via the Michael adduct.Protection and deprotection can be achieved in high yields under mild basic conditions, in protic or aprotic solvents.