331857-03-5

Basic information

• Product Name: 3-AMINO-4-DIMETHYLAMINO-THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
• Synonyms: 3-AMINO-4-DIMETHYLAMINO-THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER;Methyl 3-amino-4-dimethylamino-thieno[2,3-b]pyridine-2-carboxylate
• CAS NO: 331857-03-5
• Molecular Formula: C₁₁H₁₃N₃O₂S
• Molecular Weight: 0
• Mol File: 331857-03-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-AMINO-4-DIMETHYLAMINO-THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-4-DIMETHYLAMINO-THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER(331857-03-5)
• EPA Substance Registry System: 3-AMINO-4-DIMETHYLAMINO-THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER(331857-03-5)

Safety Data

• Hazardous Substances Data: 331857-03-5(Hazardous Substances Data)

Upstream product

• 2365-48-2 Methyl thioglycolate 
• 147992-80-1 2-chloro-4-(dimethylamino)nicotinonitrile 
• 872889-89-9 C₁₁H₁₃N₃O₂S 
• 91945-90-3 2-[1,3-bis(dimethylaminoallylidene)]malononitrile 
• 14164-26-2 α-Cyano-β-dimethylaminocrotononitrile 

Downstream Products

• 159583-14-9 3-(4-Chloro-phenyl)-9-dimethylamino-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one 
• 159583-12-7 3,4-dihydro-3-benzyl-9-dimethylaminopyrido-<3,2:4',5'>thieno<3,2-d>pyrimidin-4-one 
• 159583-15-0 9-Dimethylamino-3-p-tolyl-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one 
• 159583-13-8 9-dimethylamino-3-phenyl-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one 

Relevant articles and documents

FUSED TRICYCLIC MGLUR1 ANTAGONISTS AS THERAPEUTIC AGENTS

In its many embodiments, the present invention provides tricyclic compounds of formula I (wherein J1-J3, X, Z, and R1-R4 are as defined herein) useful as metabotropic glutamate receptor (mGluR) antagonists, part

ANTAGONISTS OF THE MGLU RECEPTOR AND USES THEREOF

The present invention discloses compounds of general formula (I) wherein X1-X4 and R1-R3 are as defined in the description. The present invention also discloses methods of treatment for pain, neurodegeneration and convulsive states in a host mammal in need thereof, and pharmaceutical compositions including those compounds.

Structure-activity relationship of triazafluorenone derivatives as potent and selective mGluR1 antagonists

SAR (structure-activity relationship) studies of triazafluorenone derivatives as potent mGluR1 antagonists are described. The triazafluorenone derivatives are non-amino acid derivatives and noncompetitive mGluR1 antagonists that bind at a putative alloste