148-83-4

Basic information

• Product Name: IMPERATORIN
• Synonyms: OSTRUTHIN;IMPERATORIN(P);OSTRUTHIN IMPERATORIN;6-[(2E)-3,7-Dimethyl-2,6-octadienyl]-7-hydroxy-2H-1-benzopyran-2-one;6-[(E)-3,7-Dimethyl-2,6-octadienyl]-7-hydroxy-2H-1-benzopyran-2-one;6-(3,7-Dimethyl-2,6-octadienyl)-7-hydroxycoumarin;6-Geranyl-7-hydroxycoumarin;Ostruthine
• CAS NO: 148-83-4
• Molecular Formula: C₁₉H₂₂O₃
• Molecular Weight: 298.38
• EINECS: 207-581-1
• Mol File: 148-83-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 117-119°
• Boiling Point: 485.3 °C at 760 mmHg
• Flash Point: 200.3 °C
• Appearance: /
• Density: 1.116 g/cm³
• Vapor Pressure: 4.84E-10mmHg at 25°C
• Refractive Index: 1.573
• Storage Temp.: ?20°C
• CAS DataBase Reference: IMPERATORIN(CAS DataBase Reference)
• NIST Chemistry Reference: IMPERATORIN(148-83-4)
• EPA Substance Registry System: IMPERATORIN(148-83-4)

Safety Data

• Hazard Codes: N
• Statements: 50
• Safety Statements: 61
• RIDADR: UN 3077 9 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 148-83-4(Hazardous Substances Data)

Usage

Definition

ChEBI: A natural product found in Peucedanum ostruthium.

InChI:InChI=1/C19H22O3/c1-13(2)5-4-6-14(3)7-8-15-11-16-9-10-19(21)22-18(16)12-17(15)20/h5,7,9-12,20H,4,6,8H2,1-3H3

Upstream product

• 93-35-6 7-hydroxy-2H-chromen-2-one 
• 106-24-1 Geraniol 
• 107052-26-6 (E)-3-(4-Benzyloxy-2-hydroxy-phenyl)-acrylic acid methyl ester 
• 31005-04-6 7-(benzyloxy)-2H-chromen-2-one 
• 107052-30-2 methyl (E)-4'-benzyloxy-2'-(3,7-dimethylocta-2,6-dienyloxy)cinnamate 
• 107052-39-1 7-Benzyloxy-6-((E)-3,7-dimethyl-octa-2,6-dienyl)-chromen-2-one 

Downstream Products

• 108-46-3 recorcinol 
• 82-71-3 styphnic acid 
• 75929-29-2 6-geranyl-7-hydroxy-8(N-4'-phenylpiperazinomethyl)coumarin 

Related news

Synthesis of IMPERATORIN (cas 148-83-4) Analogs and Their Evaluation as Acetylcholinesterase and Butyrylcholinesterase Inhibitors09/29/2019

In this study, we synthesized several imperatorin analogs using imperatorin and xanthotoxin as substrates. The anti‐cholinesterase activities of all compounds were evaluated in in vitro experiments according to the modified Ellman's method. For each synthesized compound, IC50 values for both en...detailed

Activating the pregnane X receptor by IMPERATORIN (cas 148-83-4) attenuates dextran sulphate sodium‐induced colitis in mice09/28/2019

Background and Purpose Activation of the human pregnane X receptor (PXR; NR1I2) has potential therapeutic uses for inflammatory bowel disease (IBD). Imperatorin (IMP), a naturally occurring coumarin, is the main bioactive ingredient of Angelica dahurica Radix, which is regularly used to treat th...detailed

Relevant articles and documents

PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS

The present application describes process for preparing an ortho-allylated hydroxy aryl compounds such as compounds of Formula (I) by reacting an allylic alcohol with a hydroxy aryl compound in the presence of aluminum compound selected from alumina and aluminum alkoxides and in a non-protic solvent wherein at least one carbon atom ortho to the hydroxy group in the hydroxy aryl compound is unsubstituted. The present application also includes compounds of Formula (I).

Synthesis of linear coumarins via para-Claisen rearrangement of coumarate ester derivatives: Total syntheses of suberosin, demethylsuberosin, and ostruthin

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