31005-04-6

Basic information

• Product Name: 7-(benzyloxy)-2H-chromen-2-one
• Synonyms: 7-(benzyloxy)-2H-chromen-2-one
• CAS NO: 31005-04-6
• Molecular Formula: C₁₆H₁₂O₃
• Molecular Weight: 252.26468
• Mol File: 31005-04-6.mol
• Article Data: 23

Chemical Properties

• Melting Point: 155 °C
• Boiling Point: 442.1±45.0 °C(Predicted)
• Appearance: /
• Density: 1.250±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 7-(benzyloxy)-2H-chromen-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7-(benzyloxy)-2H-chromen-2-one(31005-04-6)
• EPA Substance Registry System: 7-(benzyloxy)-2H-chromen-2-one(31005-04-6)

Safety Data

• Hazardous Substances Data: 31005-04-6(Hazardous Substances Data)

Upstream product

• 93-35-6 7-hydroxy-2H-chromen-2-one 
• 620-05-3 iodomethylbenzene 
• 4279-77-0 S-phenyl hydrogen thiomalonate 
• 52085-14-0 4-benzoxy-salicylaldehyde 
• 3769-41-3 3-Benzyloxyphenol 
• 623-47-2 propynoic acid ethyl ester 
• 100-51-6 benzyl alcohol 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 

Downstream Products

• 107052-26-6 (E)-3-(4-Benzyloxy-2-hydroxy-phenyl)-acrylic acid methyl ester 
• 93-35-6 7-hydroxy-2H-chromen-2-one 
• 26486-92-0 6-deoxyisojacareubin 
• 1416152-15-2 (E)-butyl 3-(7-(benzyloxy)-2-oxo-2H-chromen-3-yl)acrylate 
• 1417997-51-3 C₁₇H₁₆O₄ 
• 1417997-45-5 C₁₉H₂₀O₄ 
• 11037-15-3 hemiprangosine 
• 15399-67-4 Prangosine 
• 107052-40-4 7-Benzyloxy-6-((2E,6E)-3,7,11-trimethyl-dodeca-2,6,10-trienyl)-chromen-2-one 
• 107052-39-1 7-Benzyloxy-6-((E)-3,7-dimethyl-octa-2,6-dienyl)-chromen-2-one 
• 107052-35-7 (E)-3-{4-Benzyloxy-2-[((E)-but-2-enyl)oxy]-phenyl}-acrylic acid methyl ester 
• 107052-30-2 methyl (E)-4'-benzyloxy-2'-(3,7-dimethylocta-2,6-dienyloxy)cinnamate 
• 160069-11-4 methyl 4'-benzyloxy-5'-(3-methylbut-2-enyl)(3-methylbut-2-enyloxy)cinnamate 

Relevant articles and documents

Oxyprenylated Phenylpropanoids Bind to MT1 Melatonin Receptors and Inhibit Breast Cancer Cell Proliferation and Migration

Oxyprenylated compounds (i.e., ferulic acid and coumarin derivatives) demonstrate neuroprotection and anticancer properties as reported in previous studies. We have tested the affinity of oxyprenylated ferulic acid (1-4) and umbelliferone derivatives (5-1

Gold(I)-Catalyzed Intramolecular Hydroarylation of Phenol-Derived Propiolates and Certain Related Ethers as a Route to Selectively Functionalized Coumarins and 2 H-Chromenes

Methods are reported for the efficient assembly of a series of phenol-derived propiolates, including the parent system 56, and their Au(I)-catalyzed cyclization (intramolecular hydroarylation) to give the corresponding coumarins (e.g., 1). Simple syntheses of natural products such as ayapin (144) and scoparone (145) have been realized by such means, and the first of these subject to single-crystal X-ray analysis. A related process is described for the conversion of propargyl ethers such as 156 into the isomeric 2H-chromene precocene I (159), a naturally occurring inhibitor of juvenile hormone biosynthesis.

Chlorophyll-catalyzed photochemical regioselective coumarin C-H arylation with diazonium salts

This communication describes the development of a mild method for the cross-coupling of the C3-position of coumarin with an array of diazonium salts mediated by chlorophyll as a biocatalyst via visible light catalysis. A natural pigment such as chlorophyll is used as a green photosensitizer and environmentally benign catalyst. This general and easy procedure provides a transition-metal-free alternative for the formation of 3-aryl coumarin derivatives at room temperature with good to excellent yields. This journal is