148065-34-3Relevant academic research and scientific papers
Concise synthesis of enantiomers of 4-aminobutane-1,2,3-triol
Dunlap, Norma K.,Drake, John,Ward, Andrea,Salyard, Tracy L. J.,Martin, Leah
, p. 2928 - 2930 (2008/09/19)
(Chemical Equation Presented) A very efficient synthesis of (2R,3S) and (2S,3R)-4-aminobutane-1,2,3-triol has been developed using either D- or L-glucose as the starting material. A key step is the one-pot conversion of an aldehyde to an amide, the scope of which has been extended to include other carbohydrate-derived aldehydes.
1,3-dioxolane C-nucleosides: Asymmetric synthesis of four stereoisomers of 2-[2-(hydroxymethyl)-1,3-dioxolan-5-yl]-1,3-thiazole-4-carboxamide
Jinfa, Du,Fucheng, Qu,Lee Doo-won,Gary Newton,Chu Chung
, p. 8167 - 8170 (2007/10/02)
Asymmetric synthesis of four novel C-nucleosides, (2′R,5′R)-, (2′S,5′R)-, (2′S,5′S)- and (2′R,5′S)-2-[2-hydroxymethyl)-1,3-dioxolan-5-yl]-1,3-thiazole-4- carboxamide has been accomplished by the condensation of key intermediates, 2-(1R- and 1S-glycol-1-yl)-4-ethoxycarbonyl-1,3-thiazole with 2-benzoyloxy acetaldehyde dimethyl acetal.
