148119-53-3

Basic information

• Product Name: 2-Methoxy-5-(2,4,6-trioxo-tetrahydro-pyrimidin-5-ylidenemethyl)-benzenesulfonyl chloride
• CAS NO: 148119-53-3
• Molecular Weight: 344.732
• Mol File: 148119-53-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Methoxy-5-(2,4,6-trioxo-tetrahydro-pyrimidin-5-ylidenemethyl)-benzenesulfonyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methoxy-5-(2,4,6-trioxo-tetrahydro-pyrimidin-5-ylidenemethyl)-benzenesulfonyl chloride(148119-53-3)
• EPA Substance Registry System: 2-Methoxy-5-(2,4,6-trioxo-tetrahydro-pyrimidin-5-ylidenemethyl)-benzenesulfonyl chloride(148119-53-3)

Safety Data

• Hazardous Substances Data: 148119-53-3(Hazardous Substances Data)

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 49546-71-6 5-(4-methoxybenzylidene)barbituric acid 

Relevant articles and documents

CHLOROSULFONATION OF 5,5-DIPHENYLHYDANTOIN AND 5-ARYLIDENEBARBITURIC ACIDS

5,5-Diphenylhydantoin (1) by heating with chlorosulfonic acid gave a bis-sulfonyl chloride (2) in which the orientation of sulfonation is apparently meta/para.The chloride (2) was converted into 8 sulfonamides (3-10).Barbituric acid has been condensed with aromatic aldehydes to yield 18 5-arylidene derivatives (11-28).The reaction of chlorosulfonic acid with 5-benzylidenebarbituric acid (11) is discussed together with the subsequent reaction of the sulfonyl chloride with amines.The chlorosulfonation of other arylidenebarbituric acids (12-14, 22, 23, 26 and 28) has also been examined. Key words: 5,5-Diphenylhydantoin; 5-arylidenebarbituric acids; chlorosulfonation; sulfonamides; Michael addition.