148236-89-9

Upstream product

• 93-97-0 benzoic acid anhydride 
• 148236-84-4 (R)-4-((3aR,5R,6S,6aR)-6-Benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-4-benzyloxymethyl-3-(4-methoxy-phenyl)-oxazolidin-2-one 
• 148236-83-3 4-(3-O-benzyl-1,2-O-isopropylidene-α-D-xylofuranos-5-yl)-3-(4-methoxyphenyl)-4-vinyloxazolidin-2-one 
• 148236-85-5 (R)-4-((3aR,5R,6S,6aR)-6-Benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-4-benzyloxymethyl-oxazolidin-2-one 
• 148236-81-1 (3aR,5S,6S,6aR)-6-Benzyloxy-2,2-dimethyl-5-((R)-2-vinyl-oxiranyl)-tetrahydro-furo[2,3-d][1,3]dioxole 
• 106445-04-9 1-(6-benzyloxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)-2-(tert-butyldimethylsiloxy)ethanol 
• 106445-05-0 3-O-benzyl-6-O-tert-butyldimethylsilyl-1,2-O-isopropylidene-α-D-xylo-hexofuran-5-ulose 
• 98-88-4 benzoyl chloride 
• 148236-87-7 Benzoic acid (3aR,3bS,6S,6aR,7aR)-6-benzoylamino-2,2-dimethyl-5-oxo-hexahydro-furo[2',3':4,5]furo[2,3-d][1,3]dioxol-6-ylmethyl ester 
• 353796-70-0 5-C-(O-benzylhydroxylamino)-5-deoxy-5-C-(hydroxymethyl)-1,2-O-isopropilidene-β-L-idofuranose-3,6-lactone 

Relevant academic research and scientific papers

Synthesis of α-Azido Aldehydes. Stereoselective Formal Access to the Immunosuppressant Myriocin

Stereoselective preparation of an acyclic α-azido aldehyde permitted access in a few steps to a key intermediate in a formal synthesis of myriocin.

Photoinduced Formation of β-Oxy-α,α-disubstituted-α-amino Acid Derivatives from Ketoximes

(matrix presented) The first intermolecular radical addition onto ketoxime ethers is described. β-Oxygenated quaternary α-amino acid derivatives II were obtained upon irradiation of α-alkoxycarbonyl ketoxime ethers I in the presence of suitable α-alkoxy carbon radical precursors and a sensitizer.

Stereoselective access to oc-azido aldehydes and a new synthetic route to myriocin

Reaction of dichloromethyllithium with six-membered carbohydrate ketones followed by azide ion treatment furnished stereoselectively a-azido aldehydes, potential intermediates in the synthesis of a-substituted a-amino acids. The same reaction sequence applied to an acyclic ketone lOa allowed the preparation of an a-azido aldehyde 12 which could be converted in four steps into a known intermediate 14b of the total synthesis of the immunosuppressant myriocin 16. Elsevier,.

A formal synthesis of a novel immunosuppressant ISP-1 : Stereocontrolled Pd(O) catalysedcis-hydroxyamination of carbohydrate derived vinyl epoxide

Described herein are the results leading to the synthesis of ISP-1 containing an unusal α, α-disubstituted amino acid and whose immunosuppressive activity only has recently been discovered.