1484-35-1

Basic information

• Product Name: N-(2-nitrophenyl)-N-phenylacetamide
• CAS NO: 1484-35-1
• Molecular Formula: C₁₄H₁₂N₂O₃
• Molecular Weight: 256.2567
• Mol File: 1484-35-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 487.4°C at 760 mmHg
• Flash Point: 248.6°C
• Density: 1.284g/cm³
• Vapor Pressure: 1.19E-09mmHg at 25°C
• Refractive Index: 1.636
• CAS DataBase Reference: N-(2-nitrophenyl)-N-phenylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-nitrophenyl)-N-phenylacetamide(1484-35-1)
• EPA Substance Registry System: N-(2-nitrophenyl)-N-phenylacetamide(1484-35-1)

Safety Data

• Hazardous Substances Data: 1484-35-1(Hazardous Substances Data)

Upstream product

• 88-73-3 2-Chloronitrobenzene 
• 103-84-4 Acetanilid 
• 577-19-5 2-nitrophenyl bromide 
• 234075-17-3 (2-nitro-phenylsulfanyl)-acetyl chloride 
• 107922-13-4 (2-nitro-phenylsulfanyl)-acetic acid anilide 
• 609-73-4 o-nitroiodobenzene 
• 591-50-4 iodobenzene 
• 552-32-9 o-nitroacetanilide 
• 108-86-1 bromobenzene 
• 1496-76-0 N-benzoylindole 
• 409111-36-0 (2-nitro-benzenesulfonyl)-acetic acid anilide 
• 7697-37-2 nitric acid 
• 108-24-7 acetic anhydride 
• 122-39-4 diphenylamine 

Downstream Products

• 1484-40-8 N-(2-amino-phenyl)-N-phenyl-acetamide 
• 1484-39-5 2-methyl-1-phenyl-1H-benzimidazole 
• 304-81-4 Phenazin-mono-N-Oxyd 
• 119-75-5 2-nitro-N-phenylaniline 
• 1484-41-9 1-Phenyl-2-methyl-benzimidazol-3-oxid 

Relevant articles and documents

A direct, regioselective palladium-catalyzed synthesis of N-substituted benzimidazoles and imidazopyridines

Unsymmetric, N-substituted benzimidazoles and imidazopyridines can be prepared directly from 2-halonitroarenes and amides through Pd(TFA) 2/(R)-BINAP-catalyzed cross-coupling and subsequent reductive aminocyclization. This sequence can be conducted by a one-pot procedure. The method is versatile and allows the straightforward, regioselective preparation of these important nitrogen heterocycles. Unsymmetrical, N-substituted benzimidazoles can be prepared directly from 2-halonitroarenes and amides through Pd(TFA)2/(R)-BINAP-catalyzed cross-coupling and subsequent reductive aminocyclization.This sequence can be conducted by a one-pot procedure. The method is versatile and allows the straightforward, regioselective preparation of these important nitrogen heterocycles. Copyright

DBU, a highly efficient reagent for the facile regeneration of (hetero)arylamines from their acetamides and benzamides: Influence of solvent, temperature, and microwave irradiation

1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) was found to smoothly cleave the N-acetyl and N-benzoyl derivatives of carbazoles, indoles and nitroanilines quickly in refluxing methanol and the parent amines were recovered in excellent yields. Complete cleavage could also be accomplished in acetonitrile solution under reflux and also under microwave irradiation, which, however, required considerably longer periods.