1485-74-1

Upstream product

• 20989-17-7 (2S)-2-phenylglycinol 
• 94-36-0 dibenzoyl peroxide 
• 1374683-07-4 N-(S)-α-methylbenzyl-O-benzoyl hydroxylamine hydrochloride 

Downstream Products

• 1374683-00-7 N-(S)-α-methylbenzyl-O-benzylcarbonate hydroxylamine 
• 1374682-64-0 N-(S)-α-methylbenzyl-O-pivaloyl hydroxylamine 
• 1374683-04-1 N-(S)-α-methylbenzyl-O-diphenylcarbamoyl hydroxylamine 
• 1374682-67-3 N-(S)-α-methylbenzyl-O-3,5-di-tert-butylbenzoyl hydroxylamine 
• 1374682-68-4 N-(S)-α-methylbenzyl-O-2,4,6-trimethylbenzoyl hydroxylamine 
• 1374682-69-5 N-(S)-α-methylbenzyl-O-acetyl hydroxylamine 
• 1374682-77-5 N-(S)-α-methylbenzyl-O-4-methoxybenzoyl hydroxylamine 
• 1374682-78-6 N-(S)-α-methylbenzyl-O-4-dimethylaminobenzoyl hydroxylamine 
• 1374682-80-0 N-(S)-α-methylbenzyl-O-3,4,5-trimethoxylbenzoyl hydroxylamine 
• 19052-01-8 (S)-4-methyl-N-(1-phenylethyl)benzamide 
• 127104-54-5 (-)-(S)-N-(2-methylpropylidene)-1-phenylethanamine N-oxide 
• 53933-47-4 N-((1S)-1-phenylethyl)hydroxylamine 

Relevant academic research and scientific papers

Asymmetric α-oxyacylation of cyclic ketones

Reaction of cyclic ketones with chiral N-alkyl-O-acyl hydroxylamines leads to the corresponding α-oxyacylated carbonyl compound in up to 89% ee. The levels of asymmetric induction were influenced by solvent polarity, acid strength and, to a lesser extent,

Diastereoselectivity of Organometallic Additions to Nitrones Bearing Sterogenic N-Substituents

The diastereoselectivity of organometallic additions to nitrones bearing stereogenic α-arylethyl, β-methoxyalkyl, and β-(silyloxy)alkyl substituents on nitrogen has been investigated.High and complementary diastereoselectivity (90-94percent) was observed in the additions of Grignard reagents to nitrones (e.g. 22 and 23) bearing the potentially chelating β-methoxyalkyl group.However, the opposite selectivity resulted from the reaction of methylmagnesium bromide with the corresponding silyl ether (27).The relative stereochemistry of selected hydroxylamine adducts wasestablished by reduction of their phosphate and carbonate derivatives to known amines (37a,b and 39), by periodate cleavage of a β-hydroxy hydroxylamine (41b), and by various correlations (Scheme II).The high facial diastereoselectivity observed with the N-(β-methoxyalkyl)nitrones is explained by a simple chelation model (Scheme III).