148541-70-2

Basic information

• Product Name: ETHYL 5-FLUOROPYRIDINE-2-CARBOXYLATE
• Synonyms: ETHYL 5-FLUOROPYRIDINE-2-CARBOXYLATE;5-Fluoropyridine-2-carboxylic acid ethyl ester;ethyl 5-fluoropicolinate;2-Pyridinecarboxylic acid, 5-fluoro-, ethyl ester
• CAS NO: 148541-70-2
• Molecular Formula: C₈H₈FNO₂
• Molecular Weight: 169.16
• Mol File: 148541-70-2.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 234.7°C at 760 mmHg
• Flash Point: 95.744°C
• Appearance: /
• Density: 1.197g/cm³
• Vapor Pressure: 0.052mmHg at 25°C
• Refractive Index: 1.489
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: -0.59±0.10(Predicted)
• CAS DataBase Reference: ETHYL 5-FLUOROPYRIDINE-2-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 5-FLUOROPYRIDINE-2-CARBOXYLATE(148541-70-2)
• EPA Substance Registry System: ETHYL 5-FLUOROPYRIDINE-2-CARBOXYLATE(148541-70-2)

Safety Data

• Hazardous Substances Data: 148541-70-2(Hazardous Substances Data)

Usage

General Description

Ethyl 5-fluoropyridine-2-carboxylate is an organic compound with the molecular formula C8H7NO2F. It is a derivative of pyridine, with a fluorine atom at the 5-position and an ethyl ester group at the 2-position of the pyridine ring. ETHYL 5-FLUOROPYRIDINE-2-CARBOXYLATE is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. Its chemical properties make it a valuable intermediate in the production of various compounds with biological activity. Additionally, ethyl 5-fluoropyridine-2-carboxylate may also be used in research and development applications.

InChI:InChI=1/C8H8FNO2/c1-2-12-8(11)7-4-3-6(9)5-10-7/h3-5H,2H2,1H3

Upstream product

• 107504-08-5 5-fluoropicolinic acid 
• 64-17-5 ethanol 
• 41404-58-4 2-bromo-5-fluoropyridine 
• 201230-82-2 carbon monoxide 

Downstream Products

• 31181-88-1 5-fluoropicolinaldehyde 
• 802325-29-7 5-fluoro-2-hydroxylmethylpyridine 
• 1310805-69-6 5-(5-{3-isopropoxy-5-[(1-methyl-1H-pyrazol-3-yl)carbamoyl]phenoxy}pyridin-2-yl)-N-methyl-1,3,4-oxadiazole-2-carboxamide 
• 1310807-57-8 5-{3-isopropoxy-5-[(1-methyl-1H-pyrazol-3-yl)carbamoyl]phenoxy}pyridine-2-carboxylic acid 
• 1310807-59-0 ethyl {2-[(5-{3-isopropoxy-5-[(1-methyl-1H-pyrazol-3-yl)carbamoyl]phenoxy}pyridin-2-yl)carbonyl]hydrazino}(oxo)acetate 
• 1310809-56-3 ethyl 5-(5-{3-isopropoxy-5-[(1-methyl-1H-pyrazol-3-yl)carbamoyl]phenoxy}pyridin-2-yl)-1,3,4-oxadiazole-2-carboxylate 
• 1310807-58-9 3-{[6-(hydrazinocarbonyl)pyridin-3-yl]oxy}-5-isopropoxy-N-(1-methyl-1H-pyrazol-3-yl)benzamide 
• 1310809-41-6 C₂₅H₃₀N₆O₆ 
• 1149752-51-1 N-[(1R)-1-(5-fluoropyridin-2-yl)ethyl]-2-methylropane-2-sulfinamide 

Relevant articles and documents

SULFOXIMINE COMPOUND AS BROMODOMAIN PROTEIN INHIBITOR AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF

The present invention relates to a sulfoximine compound represented by formula (I) as a bromodomain protein inhibitor and a pharmaceutically acceptable salt thereof and to a preparation method, pharmaceutical composition, and medical use thereof.

P2X3, RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN

The subject invention relates to novel P2X3 receptor antagonists that play a critical role in treating disease states associated with pain, in particular peripheral pain, inflammatory pain, or tissue injury pain that can be treated using a P2X3 receptor subunit modulator.

P2X3, RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN

The subject invention relates to novel P2X3 receptor antagonists that play a critical role in treating disease states associated with pain, in particular peripheral pain, inflammatory pain, or tissue injury pain that can be treated using a P2X3 receptor subunit modulator.