14860-82-3

Usage

Uses

Used in Chemical Synthesis:
1-Chloro-4-propoxybutane is used as a reagent in chemical synthesis for its reactive nature, enabling the creation of various compounds and materials.
Used in Scientific Research:
1-Chloro-4-propoxybutane is used as a research tool in scientific studies, where its unique properties and reactivity can be explored and utilized for advancing knowledge in chemistry and related fields.
Used in Pharmaceutical Industry:
1-Chloro-4-propoxybutane is used as an intermediate in the synthesis of pharmaceutical compounds, contributing to the development of new drugs and medications.
Used in Material Science:
1-Chloro-4-propoxybutane is used as a component in the development of new materials, such as polymers and coatings, due to its ability to react with other compounds and form stable structures.
Safety Considerations:

InChI:InChI=1/C7H15ClO/c1-2-6-9-7-4-3-5-8/h2-7H2,1H3

Upstream product

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• 10297-05-9 1-chloro 4-iodobutane 

Relevant academic research and scientific papers

ON THE MECHANISM OF SELECTIVE CHLORINATION OF ETHERS WITH SULFURYL CHLORIDE IN THE DARK

Alkyl 4-chlorobutyl ethers reacted in the dark with an excess of sulfuryl chloride at 70-85 deg C (bath) to afford α,β,β-trichlorinated ethers.The reactions were accelerated 3- to 6-fold by N,N-dimethyloctylammonium salts (0,12 to 1 mmol/mol ether).This catalyst promoted decomposition of sulfuryl chloride to chlorine and sulfur dioxide and thereby caused serious loss of sulfuryl chloride.The proportions of chlorination at α or α1 position were identical in the catalyzed or uncatalyzed version and depended on inductive effects, correlating well with Taft's linear free energy relationship log k/kref=ρ*?* for R = H, Me, Et, Pr in RCH2O(CH2)4Cl with ρ* = -2.6 +/- 0.1.The overall reactivity of ethers appears to vary like the nucleophilicity of the ether oxygen.It is concluded that hydride abstraction occurs indirectly, probably involving a chloroxonium ion pair.

LONG-ACTING CONTRACEPTIVE AGENTS: ESTERS OF NORETHISTERONE WITH ALKOXY- AND HALOGENO-SUBSTITUTED CARBOXYLIC ACIDS

The chemical synthesis and physical data of several new esters of norethisterone (17α-ethynyl-17β-hydroxyestr-4-en-3-one) are reported, which contain either a chloro- or an alkoxy-group as a substituent in the acid side-chain.