148651-35-8 Usage
Uses
2-Chlorophenylzinc iodide is an organozinc compound, which can be used as a reactant in Negishi cross-coupling reaction to construct carbon-carbon bonds by reacting with organic halides using nickel or palladium catalysts. It can also be utilized as a reactant to prepare: Arylmethanes via rhodium-catalyzed cross-coupling reaction with methyl halides. (2-chlorobenzyl)trimethylsilane by Rh-catalyzed cross-coupling reaction with (iodomethyl)trimethylsilane. Dichloro biphenyl by palladium catalyzed oxidative homocoupling reaction using N-chlorosuccinimide (NCS) or O2 as the oxidant.
Check Digit Verification of cas no
The CAS Registry Mumber 148651-35-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,8,6,5 and 1 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 148651-35:
(8*1)+(7*4)+(6*8)+(5*6)+(4*5)+(3*1)+(2*3)+(1*5)=148
148 % 10 = 8
So 148651-35-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H4Cl.HI.Zn/c7-6-4-2-1-3-5-6;;/h1-4H;1H;/q;;+1/p-1/rC6H4ClIZn/c7-5-3-1-2-4-6(5)9-8/h1-4H
148651-35-8Relevant articles and documents
Ultrasound-Promoted Synthesis of Arylzinc Compounds Using Zinc Powder and Their Application to Palladium(0)-Catalyzed Synthesis of Multifunctional Biaryls
Takagi, Kentaro
, p. 469 - 472 (1993)
Arylzinc compounds containing electron-withdrawing groups such as CO2CH3, CON(CH3)2, CN, Br, Cl, or CF3 at ortho position were prepared readily by the ultrasound-promoted reaction of aryl iodides with zinc powder, which were applied to palladium(0)-catalyzed cross-coupling with aryl halides to afford unsymmetrical and multifunctional biaryls in good yields.
