148683-93-6Relevant articles and documents
Synthesis, in vitro anti-inflammatory and cytotoxic evaluation, and mechanism of action studies of 1-benzoyl-β-carboline and 1-benzoyl-3-carboxy-β-carboline derivatives
Yang, Mei-Lin,Kuo, Ping-Chung,Hwang, Tsong-Long,Chiou, Wen-Fei,Qian, Keduo,Lai, Chin-Yu,Lee, Kuo-Hsiung,Wu, Tian-Shung
experimental part, p. 1674 - 1682 (2011/04/16)
In the present study, various 1-substituted and 1,3-disubstituted β-carboline derivatives were synthesized by a modified single-step Pictet-Spengler reaction. The compounds were examined for cytotoxicity and anti-inflammatory activity, as measured by the
A versatile route to the synthesis of 1-substituted β-carbolines by a single step Pictet-Spengler cyclization
Yang, Mei-Lin,Kuo, Ping-Chung,Damu, Amooru G.,Chang, Ren-Jie,Chiou, Wen-Fei,Wu, Tian-Shung
, p. 10900 - 10906 (2007/10/03)
A one-step conversion of l-tryptophan and activated aldehydes (1,2-dicarbonyl compounds) directly to 1-substituted β-carbolines without formation of the tetrahydro derivatives under modified Pictet-Spengler conditions was described. Moreover, a practical