14871-92-2

Usage

Uses

Used in Pharmaceutical Industry:
(2,2'-BIPYRIDINE)DICHLOROPALLADIUM(II) is used as a catalyst in the synthesis of complex organic molecules for pharmaceutical applications. Its high reactivity and selectivity contribute to the efficient production of compounds that are vital in the development of new drugs and medicinal agents.
Used in Materials Science:
In the materials science field, (2,2'-BIPYRIDINE)DICHLOROPALLADIUM(II) is utilized as a catalyst for the synthesis of advanced materials with specific properties. Its role in cross-coupling reactions allows for the creation of materials with tailored characteristics for use in various high-tech applications, such as electronics, optoelectronics, and nanotechnology.
Used in Organic Synthesis:
(2,2'-BIPYRIDINE)DICHLOROPALLADIUM(II) is employed as a catalyst in organic synthesis for the formation of carbon-carbon and carbon-heteroatom bonds. Its presence in cross-coupling reactions facilitates the construction of molecular frameworks that are crucial in the synthesis of natural products, pharmaceuticals, and other organic compounds with biological activity.

Upstream product

• 366-18-7 [2,2]bipyridinyl 
• 7440-05-3 palladium 
• 15617-18-2 bis(benzonitrile)palladium(II) dichloride 
• 10025-98-6 potassium tetrachloropalladate(II) 
• 110173-82-5 PdCl₂(P(C₆H₅)(C₅H₄N)2)2 
• 52518-95-3 CuCl₂(C₄H₉NH₂)2 
• 13869-70-0 Ni(aniline)2Cl₂ 
• 128-09-6 N-chloro-succinimide 
• 301840-93-7 PdCl(CONCH₂CH₂OCH₂CH₂)(2,2'-dipyridine) 
• 7782-50-5 chlorine 
• 301840-91-5 PdCl(CON(CH₂)5)(2,2'-dipyridine) 
• 301840-96-0 Pd(CONCH₂CH₂OCH₂CH₂)2(2,2'-dipyridine) 
• 301840-95-9 Pd(CON(CH₂)5)2(2,2'-dipyridine) 
• 999-78-0 4,4-dimethyl-2-pentyne 

Downstream Products

• 220171-63-1 Pd((C₅H₄N)2)(N(P(O)(C₆H₅)2)P(S)(C₆H₅)2)⁽¹⁺⁾*PF₆^(1-)=[Pd((C₅H₄N)2)(N(P(O)(C₆H₅)2)P(S)(C₆H₅)2)]PF₆ 
• 220171-66-4 Pd((C₅H₄N)2)(N(P(O)(C₆H₅)2)P(Se)(C₆H₅)2)⁽¹⁺⁾*PF₆^(1-)=[Pd((C₅H₄N)2)(N(P(O)(C₆H₅)2)P(Se)(C₆H₅)2)]PF₆ 
• 113872-71-2 PdCl₂(C₆H₄OMe-p)NCHCHN(C₆H₄OMe-p) 
• 88291-83-2 [Pd₂Cl₂(1,2,3,4-tetraphenylbuta-1,3-diene-1,4-diyl)(2,2'-bipyridine)2] 
• 7440-05-3 palladium 
• 55172-29-7 thallium chloride 
• 301840-91-5 PdCl(CON(CH₂)5)(2,2'-dipyridine) 
• 6091-44-7 piperidine hydrochloride 
• 301840-95-9 Pd(CON(CH₂)5)2(2,2'-dipyridine) 
• 275369-89-6 [(C₆F₅)2Pd(C₃H₃N₂)2Pd(C₅H₄NC₅H₄N)] 
• 675201-51-1 Pd(O₂CC₆H₄CF₃)2(2,2'-bipyridine) 
• 195372-97-5 Pd((C₅H₄N)2)(C₆H₅C(O)NCH(CH(CH₃)2)COO) 
• 160491-46-3 [Pd(CH(COMe)C(O)NPh)(2,2-bipyridyl)] 
• 1079321-06-4 [Pd(2,2'-bipyridine)(N-(2-hydroxyphenyl)-p-toluenesulfonamide(-2H))] 

Relevant academic research and scientific papers

Multi-target heteroleptic palladium bisphosphonate complexes

Abstract: Bisphosphonates are the most commonly prescribed drugs for the treatment of osteoporosis and other bone illnesses. Some of them have also shown antiparasitic activity. In search of improving the pharmacological profile of commercial bisphosphona

Mechanistic study on the gas-phase generation of "rollover"- Cyclometalated [M(bipy - H)]+ (M = Ni, Pd, Pt)

"Rollover"-cyclometalated [Pt(bipy - H)]+ (bipy = 2,2′-bipyridine) can be easily generated in the gas phase via HX elimination brought about by collision-induced dissociation (CID) of the cationic complexes [Pt(X)(bipy)]+ with X = CH3, Cl; the latter as well as other [M(X)(bipy)]+ complexes (M = Ni, Pd; X = CH3, F, Cl, Br, I, OAc) are accessible by electrospray ionization mass spectrometry. For the nickel and palladium methyl complexes [M(CH 3)(bipy)]+, upon CID, no cyclometalation occurs; rather, homolytic cleavage of the M-CH3 bond takes place. The related chloro complexes [M(Cl)(bipy)]+ (M = Ni, Pd) undergo competitive eliminations of HCl and Cl upon CID, and the branching ratios depend strongly on the collision energy. On the basis of DFT calculations, this metal- and ligand-controlled behavior is a consequence of the rather different energetic requirements for the direct loss of X versus elimination of HX (X = CH 3, Cl). Deuterium-labeling experiments reveal that formation of CH4 and HCl is only for the platinum complexes due to a genuine "rollover" cyclometalation process, i.e., selective abstraction of a hydrogen atom from the C(3)-position of bipy. In the series of halo-substituted complexes [Ni(X)(bipy)]+ (X = F, Cl, Br, I), the Ni-X bond strength decreases in the sequence F > Cl > Br > I. For X = F, one observes the elimination of HF, which benefits from the particular stability of this molecule; the hydrogen atom in HF is mostly (>90%) abstracted from position C(6) with + undergoes competitive losses of HCl and Cl upon collision with Xe, and for X = Br and I only homolytic Ni-X bond cleavage takes place. In the elimination of HCl from [Ni(Cl)(bipy)]+, >60% of the hydrogen atoms originate from C(3), and the remaining from C(4,5,6), as inferred from deuterium-labeling experiments. The acetate complexes [Ni(OAc)(bipy)]+ and [Pd(OAc)(bipy)]+ exhibit eliminations of neutral AcO?, and at elevated collision energies, decarboxylation occurs. C-H bond activation resulting in the formation of HOAc is absent at the detection limit.

A model study of alternative approach toward a class of palladium(II) based self-assembly

A different approach developed for the preparation of palladium(II) based complexes [(Pd(bpy))x(L)y](NO3) 2x is modelled by using 4-phenylpyridine as ligand (L = 1). Various solvent systems are inspected to opti

Reduction of α,β-unsaturated carbonyl compounds by palladium(II) and nickel(II) complexes having nitrogen-containing ligands

Catalytic reduction reactions of α,β-unsaturated carbonyl compounds by palladium(II) and nickel(II) complexes with N,N-dimethylammine borane are studied. Palladium and nickel complexes with nitrogen donor ligands such as 2,2′-bipyridine (bpy) and N,N′-tetramethylethylenediamine are found to be effective catalysts. In the case of [Pd(bpy)Cl2] selective double bond reduction is observed. Comparative results of palladium(II)- and nickel(II)-catalysed reactions are presented.

Synthesis, Characterization, and Cytotoxicity of Palladium(II) Complexes with Diimine/Diamine and N-Carbonyl-L-Phenylalanine Dianion

Six palladium(II) complexes, [Pd(bipy)(Bzphe-N,O)] (I-a), [Pd(bipy)(p-Mbzphe-N,O)]·2H2O (I-b), [Pd(bipy)(p-Nbzphe-N,O)]·2H2O (I-c), [Pd(phen)(Bmined by X-ray diffraction. The cytotoxicity test indicates that the complexes exert cytot

Mixed-matrix materials using metal-organic polyhedra with enhanced compatibility for membrane gas separation

Discrete metal-organic polyhedra (MOPs) containing copper(ii), palladium(ii), and iron(ii) nodes were synthesized as fillers for mixed-matrix materials (MMMs) with a polyvinylidine fluoride (PVDF) polymer phase and contrasted against an MMM containing a metal-organic framework, MOF-5. When a given MOP was soluble in the precursor solutions, the resulting MMMs were thin, flexible, and homogeneous based on microscopy and SEM imaging. Analogous MMM formation using either insoluble MOPs or the inherent insoluble MOF-5 showed a higher degree of phase separation and inhomogeneity. Even when a MOP was not fully soluble, a significant particle size decrease was observed in contrast to the MOF-5 materials wherein the crystallites remained largely intact. This is a consequence of solubilizing the MOP fillers into the polymer solvent. The crystallinity and thermal stabilities of the MMMs were compared to pure PVDF using powder X-ray diffraction, and differential scanning calorimetry, indicating that the incorporation of MOPs both decreased overall crystallinity as well as increased thermal stability. In addition, MMMs containing PdMOP and FeMOP showed improved gas permeabilities relative to pure PVDF for H2, N2, CH4, and CO2, with the 10 wt% FeMOP membrane more selective for CO2 over N2 and H2.

Perfluoroalkylation of Square-Planar Transition Metal Complexes: A Strategy to Assemble Them into Solid State Materials with a π-π Stacked Lamellar Structure

Formation of π-π stacked lamellar structure is important for high performance organic semiconductor materials. We previously demonstrated that perfluoroalkylation of aromatics and heteroaromatics was one of the strategies to design organic crystalline materials with π-π stacked lamellar structures while improving air stability as a result of the strong electron withdrawing ability of perfluoroalkyl substituents. Square-planar transition metal complexes with large π-conjugated ligands are also an important category of semiconductor materials. We have perfluoroalkylated square-planar transition metal complexes, leading to the formation of a π-π stacked lamellar crystal packing motif in the solid state. Here we report six crystal structures of Pd and Pt complexes with bis-perfluorobutylated catechol ligand as one of the two ligands that bonds to the metal centers. This structural design possesses similar molecular topology when compared to perfluoroalkylated aromatics and heteroaromatics we have reported previously, again, demonstrating the steering power of the perfluoroalkyl substituents in engineering organic and organometallic solid state materials.

Synthesis of new ultrasonic-assisted palladium oxide nanoparticles: an in vitro evaluation on cytotoxicity and DNA/BSA binding properties

Better solubility and improved toxicity of palladium complexes compared with cisplatin were major reasons for synthesis of novel Pd(II) complex, [Pd(8Q)(bpy)]NO3 (8Q=8-hydroxyquinolinate, bpy=2,2′-bipyridine). Interaction between the [Pd(8Q)(bp

Mixed neutral compounds of palladium(II) and platinum (II) chelated by diolato(2-) and di-imine ligands

The synthesis and characterization are described for compounds abbreviated (a) 1-5: [Pd(phen)(OO)], where OO = the dianion from 1,2-ethanediol (1), (+)-1,2-propanediol (2), (±)-2,3-butanediol (3), (-)-1,2-butanediol (4), catechol (5); (b) the sulphur analogue (6) [Pd(phen)(SCH2CH2S)], from ethane-1,2-dithiol; (c) the platinum analogue (7) [Pt(phen)(OCH2CH2O)]; (d) the 2,2′-bipyridyl analogue (8), [Pd(bipy)(OCH2CH2O)] (phen = 1,10-phenanthroline and bipy = 2,2′-bipyridyl).

Preparation and Interconversion of Dimeric Di-μ-hydroxo and Tri-μ-hydroxo Complexes of Platinum(II) and Palladium(II) with 2,2'-Bipyridine and 1,10-Phenanthroline

Treatment of with AgNO3 in acetone gives the nitrato complexes .The palladium analogues were prepared from in dilute nitric acid.Dissolution of (M=Pd or Pt) in water results in the formation of the hydroxo-bridged dimers 2 plus nitric acid.Reaction of with AgNO3 in water gives 2 directly as the sole product.The dimers are resistant to substitution, although prolonged heating in aqueous nitric acid reforms .The dimers add 1 mol of OH(1-) to form the very stable trihydroxo-bridged compounds (1+) (M=Pt, deep red; M=Pd, deep yellow) where each metal is five-co-ordinate.These complexes are slowly cleaved by hydroxide to give , which was also prepared either by base hydrolysis or by reaction of with Ag2O.Addition of HX (X=NO3 or ClO4) to affords (1+), (2+) or at pH 8, 4, and 1 respectively.The complexes have been characterised by i.r., u.v., and n.m.r. (195Pt, 13C, and 1H) spectroscopy.