148857-53-8

Basic information

• Product Name: 3-amino-1-(p-methoxyphenyl)-1-propanol
• Synonyms: 3-amino-1-(p-methoxyphenyl)-1-propanol
• CAS NO: 148857-53-8
• Molecular Weight: 181.235
• Mol File: 148857-53-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 3-amino-1-(p-methoxyphenyl)-1-propanol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-amino-1-(p-methoxyphenyl)-1-propanol(148857-53-8)
• EPA Substance Registry System: 3-amino-1-(p-methoxyphenyl)-1-propanol(148857-53-8)

Safety Data

• Hazardous Substances Data: 148857-53-8(Hazardous Substances Data)

Upstream product

• 104-92-7 1-bromo-4-methoxy-benzene 
• 33994-11-5 α-Bromoethyl p-methoxaphenyl ketone 
• 100-66-3 methoxybenzene 
• 2632-13-5 2-Bromo-4'-methoxyacetophenone 
• 3672-47-7 3-oxo-3-(4'-methoxyphenyl)propanenitrile 
• 144172-56-5 3-benzylamino-1-(p-methoxyphenyl)-1-propanol 

Downstream Products

• 1467719-98-7 3-isothiocyanato-1-(4-methoxyphenyl)propan-1-ol 
• 1467719-99-8 1-{3-hydroxy-3-(4-methoxyphenyl)propyl}-3-methylthiourea 
• 1467720-00-8 1-{3-hydroxy-3-(4-methoxyphenyl)propyl}-3-isopropylthiourea 
• 1467720-01-9 1-{3-hydroxy-3-(4-methoxyphenyl)propyl}-3-phenylthiourea 
• 634915-21-2 2,4-dichloro-6-[3'-hydroxy-3'-(4''-methoxyphenyl)propylamino]pyrimidine 
• 634915-17-6 4,6-dichloro-2-[3'-hydroxy-3'-(4''-methoxyphenyl)propylamino]pyrimidine 

Relevant articles and documents

Rapid Access to γ-Amino-α-aryl Alcohol Scaffolds via an Enamine-Based Heck Coupling

The γ-amino-α-aryl alcohol is a key functional group for the design of inhibitors directed toward a critical family of metabolic enzymes. Here we report the transformation of simple aryl halides to a highly functionalized benzyl (3-oxo-3-arylpropyl)carbamate intermediate that can rapidly be converted to a high value γ-amino-α-aryl alcohol. This chemistry is realized through a two-step process involving an enamine-based Heck coupling (EBHC) followed by a one-pot catalytic Cbz-deprotection and ketone reduction of EBHC products.

Synthesis and Nrf2 activating ability of thiourea and vinyl sulfoxide derivatives

Thiourea and vinyl sulfoxide derivatives were designed based on the structures of sulforaphane and gallic acid, prepared and tested for HO-1 inducing activity as a measure of Nrf2 activation, and inhibitory effect on NO production as a measure of anti-inf

Substituent Effects on the Ring-chain Tautomerism of 1,3-Oxazines

The aryl substituents at positions 4 and 6 do not exert observable electronic effects on the ring-chain tautomeric ratios of 2,4- or 2,6-diarylsubstituted-tetrahydro-1,3-oxazines.On the other hand, the electronic effect of the 2-aryl substituent is marked