148869-74-3

Basic information

• Product Name: 4H-1,2,4-Triazol-4-amine, N-(4-bromophenyl)-
• CAS NO: 148869-74-3
• Molecular Formula: C8H7BrN4
• Molecular Weight: 239.074
• Mol File: 148869-74-3.mol

Chemical Properties

• CAS DataBase Reference: 4H-1,2,4-Triazol-4-amine, N-(4-bromophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1,2,4-Triazol-4-amine, N-(4-bromophenyl)-(148869-74-3)
• EPA Substance Registry System: 4H-1,2,4-Triazol-4-amine, N-(4-bromophenyl)-(148869-74-3)

Safety Data

• Hazardous Substances Data: 148869-74-3(Hazardous Substances Data)

Upstream product

• 148869-73-2 4-[N-acetyl-N-(4-bromophenyl)amino]-4H-1,2,4-triazole 
• 350-46-9 4-Fluoronitrobenzene 
• 148869-67-4 4-nitrophenyl(1,2,4-triazol-4-yl)amine 
• 148869-72-1 4-[N-acetyl-N-(4-aminophenyl)amino]-4H-1,2,4-triazole 
• 148869-71-0 4-[N-acetyl-N-(4-nitrophenyl)amino]-4H-1,2,4-triazole 

Relevant articles and documents

Triazolylated teritiary amine compound or salt thereof

A triazolylated tertiary amine compound represented by general formula (I) or a salt thereof, having an aromatase inhibitory activity and being useful for preventing and treating breast cancer, mastopathy, endometriosis, prostatomergaly, etc., wherein A represents a single bond, lower alkylene or carbonyl; B represents lower alkyl, aryl, a 5- or 6-membered heterocyclic group, or a bicyclic fused heterocyclic group; D represents aryl, a 5- or 6-membered heterocyclic group, or a bicyclic fused heterocyclic group; and E represents 4H-1,2,4-triazolyl, 1H-1,2,4-triazolyl or 1H-1,2,3-triazolyl.

Studies on aromatase inhibitors. I. Synthesis and biological evaluation of 4-amino-4H-1,2,4-triazole derivatives

Various 4-N-substituted amino-4H-1,2,4-triazole derivatives were synthesized and evaluated for aromatase-inhibitory activity (in vitro) and for pregnant mare serum gonadotropin (PMSG)-induced estrogen synthesis- inhibitory activity (in vivo). The 4-(4-cya