1489-55-0

Upstream product

• 27772-62-9 ethyl 2-formylpropionate 
• 105-37-3 Ethyl propionate 
• 54843-13-9 3-hydroxy-2-methylacrylic acid ethyl ester 
• 1523-87-1 Ethyl 2-formyl-2-methyl-5-oxohexanoate 
• 105837-97-6 6-bromo-8-methyl-1,4-dioxa-spiro[4.5]decane-8-carboxylic acid ethyl ester 

Downstream Products

• 67133-00-0 1-Methyl-4-oxo-5-phenylselanyl-cyclohex-2-enecarboxylic acid ethyl ester 
• 139599-38-5 (1S,4R)-4-(1-Ethoxy-2-iodo-ethoxy)-1-methyl-cyclohex-2-enecarboxylic acid methyl ester 
• 139599-55-6 (3S,6R)-6-(1-Ethoxy-2-iodo-ethoxy)-3-methyl-3-prop-1-ynyl-cyclohexene 
• 139599-51-2 (1S,4R)-4-(1-Ethoxy-ethoxy)-1-methyl-cyclohex-2-enecarbaldehyde 
• 139599-53-4 (3S,6R)-6-(1-Ethoxy-ethoxy)-3-methyl-3-prop-1-ynyl-cyclohexene 
• 139599-52-3 (3S,6R)-6-(1-Ethoxy-ethoxy)-3-ethynyl-3-methyl-cyclohexene 
• 57246-97-6 4-hydroxy-1-methylcyclohex-2-enecarboxylic acid 
• 139599-37-4 methyl 4α-hydroxy-1β-methylcyclohex-2-enecarboxylate 
• 139599-54-5 4β-methyl-4α-propynylcyclohex-2-en-1α-ol 
• 139599-50-1 4α-hydroxy-1β-methylcyclohex-2-enecarbaldehyde 
• 67394-30-3 1-Methyl-cyclohexen-⁽²⁾-ol-⁽⁴⁾-carbonsaeure-aethylester 
• 52008-71-6 1-methyl-4-oxo-2,5-cyclohexadiene-1-carboxylic acid ethyl ester 
• 1489-56-1 1-methyl-1,3-cyclohexadiene 
• 57246-98-7 4-Hydroxy-1,4-dimethyl-cyclohex-2-enecarboxylic acid 

Relevant academic research and scientific papers

MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEREOF

Non-steroidal compounds are provided which are useful in treating diseases associated with modulation of the glucocorticoid receptor, AP-1, and/or NF-?B activity including obesity, diabetes, inflammatory and immune diseases, and have the structure of formula (I) or an enantiomer, a diastereomer, a pharmaceutically acceptable salt, or hydrate thereof, where J is selected from NR1 or C(R4)(R4a); K is selected from NR2 or C(R5)(R5a); L is selected from NR3 or C(R6)(R6a); and A, X, Y, R1, R2, R3, R4, R4a, R5, R5a, R6, R6a, R8, R10, R11, and n are defined herein. Also provided are pharmaceutical compositions and methods of treating obesity, diabetes and inflammatory or immune associated diseases comprising said compounds.