148902-16-3Relevant academic research and scientific papers
Novel Efficient Synthesis of 1-Ethoxyvinyl Esters Using Ruthenium Catalysts and Their Use in Acylation of Amines and Alcohols: Synthesis of Hydrophilic 3'-N-Acylated Oxaunomycin Derivatives
Kita, Yasuyuki,Maeda, Hiroshi,Omori, Kana,Okuno, Takayuki,Tamura, Yasumitsu
, p. 2999 - 3006 (2007/10/02)
A novel and efficient synthesis of 1-ethoxyvinyl esters 3a-i from carboxylic acids 4a-i and ethoxyacetylene 5 by using a catalytic amount of ruthenium complex 2> 6f has been developed.These reagents reacted smoothly with amines and alcohols to give the corresponding N- and O-acylated compounds in excellent yields.This acylation method has been applied to the synthesis of hydrophilic 3'-N-acylated oxaunomycin derivatives 13a,b.
RHODIUM(II) CATALYZED CYCLIZATION OF DIAZO THIOCARBONYL COMPOUNDS FOR HETEROCYCLIC SYNTHESIS
Padwa, Albert,Kinder, Frederic R.,Nadler, William R.,Zhi, Lin
, p. 367 - 383 (2007/10/02)
The mesoionic thioisomuenchnone system was prepared from the rhodium(II) acetate catalyzed cyclization of a diazothioamide and was found to undergo smooth 1,3-dipolar cycloaddition with N-phenylmaleimide.In contrast to this system, the rhodium(II) reaction of α-diazo-β-oxo ester containing a thiocarbonyl group produced a cyclic thiocarbonyl ylide which extruded sulfur from a transient episulfide intermediate.
